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Showing 1 to 4 of 4 for “"orphan drugs"”.

  1. Orphan Drugs: Designations, Approvals, and Prices in the US

    … dissertation assessed the characteristics of orphan drug designations and approvals and the factors associated with the time lag between orphan designation and approval in the US from 1983 to 2021. It also evaluated the treatment cost of orphan and non-orphan drugs and factors explaining the …

    chapman Repository record for Orphan Drugs: Designations, Approvals, and Prices in the US (opens in a new tab)

  2. Orphan drugs : future viability of current forecasting models, in light of impending changes to influential market factors

    … were conducted to establish a baseline for how orphan drug forecasting is currently undertaken by financial market and industry analysts with the intention of understanding the variables typically accounted for in such a model. A literature search formed the basis of subsequent interviews …

    mit Repository record for Orphan drugs : future viability of current forecasting models, in light of impending changes to influential market factors (opens in a new tab)

  3. Addressing the Needs of Patients with Rare Diseases in Canada: An Evaluation of Orphan Drug Incentives

    … is currently uncertain whether or not a Canadian orphan drug policy will be given further consideration any time in the near future, this thesis seeks to consider the potential impact that three different orphan drug incentives could be expected to have in Canada. Specifically, market exclusivity, …

    sask Repository record for Addressing the Needs of Patients with Rare Diseases in Canada: An Evaluation of Orphan Drug Incentives (opens in a new tab)

  4. Analytics for financing drug development

    … drug development for drug royalties of approved drugs, it has yet to be utilized at earlier stages. This thesis starts by extending the model of drug development proposed by Fernandez et al. (2012). These extensions significantly influence the resulting performance and optimal securitization …

    mit Repository record for Analytics for financing drug development (opens in a new tab)