Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"origin firings"”.
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Investigating Checkpoint Kinases 1/2 As Novel Therapeutic Targets In Head and Neck Squamous Cell Carcinoma
… of Chk1 kinase led to aberrant increase in origin of replication firings in the sensitive, but not resistant cells and that loss of cdk2 or treatment with Roscovitine rescues the lethal phenotype seen in the sensitive cells upon Chk1 inhibition. These results suggest that exquisite …