Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"organotypic slice cultures"”.
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Modelling neuroimmune interactions using organotypic slice cultures
… (BCG) on neural tissue using the model of organotypic hippocampal slice cultures; an in vitro model that overcomes the previously mentioned obstacles. The study sought to expound on immunological and electrophysiological responses to the infection. A viable and moderate BCG infection was …
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The Mechanisms of Tau Entry to the Cytosol
… low concentrations of tau in 2D neurons and 3D organotypic slice cultures. Conversely, cholesterol supplementation or overexpression of the cholesterol transporter protein NPC1 reduced entry and almost completely blocked seeded aggregation. My findings establish entry to the cytosol as …
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Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena
… Ca2+ entry to the cell in murine primary cultures and hippocampal slice cultures. Using different pharmacological approaches, we demonstrate, that ER fission is triggered independently on Ca2+ from ER stores. Subsequently, we show that mild hypothermia, reported to be protective in …