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Showing 1 to 3 of 3 for “"organotypic culture models"”.
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Airway Epithelium Organotypic Culture Models as a Platform for Adverse Outcome Pathway Assessment of Engineered Nanomaterials
… have used young, healthy animals or cell lines cultured toward a “Normal” phenotype and thus did not address the possibility of increased AgNP toxicity in asthmatics. In the present studies, we used organotypic cultures derived from murine tracheal epithelial cells (MTEC) as a high-content in …
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Cooperative Invasion Between Tumor Cell Subpopulations
… populations of cells yet traditional metastasis models focus on the ability of a rare population of neoplastic cells to autonomously invade past the basement membrane surrounding the tumor, intravasate into blood vessels and disseminate throughout the body to colonize foreign tissues. We …
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Multi-Cellular Organotypic Liver Models for the Investigation of Chemical Toxicity and Liver Fibrosis
… microarchitecture of the organ. In vitro liver models provide insights into the role of each cell type and perturbations upon external stimuli. Despite the dissimilarities to in vivo and rapid dedifferentiation, most liver studies utilize hepatocyte monocultures. These models lack heterotypic …