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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 104 for “"organogenesis"”.
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Quantitative genetic analysis of maize organogenesis
… both purposes. Maize tassel, ear, and leaf organogenesis, although divergent in position on the plant, are hypothesized to share many of the same regulating genomic components. Insights into the genes regulating leaf, ear, and tassel morphology have implications for our understanding of …
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Cardiac Organogenesis: 3D Bioscaffolds, Bioenergetics and Regeneration
… the field of cardiac transplantation in terms of organogenesis, bioenergetics, and regeneration. The main goal through tissue bioengineering is to regenerate and salvage discarded hearts through organogenesis, or to lengthen the total organ preservation time such that organs would not be thrown …
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A THREE DIMENSIONAL MODEL OF HUMAN HEPATO-BILIARY ORGANOGENESIS
… 3D in vitro model recapitulating hepato-biliary organogenesis. This model can serve as a tool to study liver development, congenital liver diseases, develop novel therapeutic strategies, drug development and toxicity, and provide information to guide research towards creating functional liver …
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Zebrafish Posterior Lateral Line Organogenesis Regulation by Notch Signaling
Organ morphogenesis depends on the precise orchestration of cell migration, cell fate specification and cell shape chages. Results in this thesis demonstrate that Notch signaling is an integral part of the feedback loop between Wnt and Fgf signaling that underlies the self‐organization of …
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Defining The Molecular Networks Necessary For Thymus Fate and Organogenesis
… notion that <em>Tbx1 </em>is required for thymus organogenesis, we have shown that ectopic expression of <em>Tbx1 </em>in thymic epithelial cells (TECs) suppresses FOXN1, inhibits TEC proliferation and arrests TEC differentiation, suggesting <em>Tbx1</em> must be tightly regulated in the …
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Organogenesis of the Female Reproductive System of an Aedine Mosquito
Made available in DSpace on 2014-12-09T20:27:26Z (GMT). No. of bitstreams: 1 6901426.pdf: 5217803 bytes, checksum: ae84a5a8878554c02175f1c8027f6e4d (MD5) Previous issue date: 1968
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Notch signaling and cell cycle inhibitor regulation in pituitary organogenesis
The pituitary is plastic organ whose hormone cell number can fluctuate depending on physiologic need. Alterations in pituitary cell expansion can lead to disorders such as pituitary hyperplasia or tumors, which have a high prevalence in the human population. Precise control of cell cycle …
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Identification of mesenchymal genes involved in prostate organogenesis by LongSAGE analysis
Growth and development of the prostate are regulated by androgens and mesenchymalepithelial interactions. Prostate growth starts in the embryo, continues throughout neonatal life, and is completed at puberty. The male and female embryonic urogenital sinus (UGS) both contain a prostate precursor, …
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The role of the transcription factor JAGGED in early floral organogenesis
Initiation of organ primordia from pools of undifferentiated cells requires coordinated cytoplasmic growth, oriented cell wall extension, and cell cycle progression. It is debated which of these processes are primary drivers for organ morphogenesis and directly targeted by developmental regulators. …
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Imaginal Organogenesis in Mosquitoes as Affected by Sequential Temperatures: Gonadal Development
Made available in DSpace on 2014-12-11T18:05:36Z (GMT). No. of bitstreams: 1 7121196.pdf: 4632174 bytes, checksum: 2f977ff632d1b2bf1bd80927edd8f4e0 (MD5) Previous issue date: 1971
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Enforced Expression of Tbx1 In Fetal Thymic Epithelial Cells Antagonizes Thymus Organogenesis
… cells antagonizes</strong></p> <p><strong>thymus organogenesis</strong></p> <p>Kim T. Cardenas</p> <p>The thymus and parathyroid glands originate from organ-specific domains of 3rd pharyngeal pouch (PP) endoderm. At embryonic day 11.5 (E11.5), the ventral thymus and dorsal parathyroid domains can …
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Multi-omics characterisation of mouse gastrulation and organogenesis at single-cell resolution
… changes during mouse gastrulation and early organogenesis. However, the precise molecular mechanisms that control cell fate decisions are still poorly understood. Therefore, my PhD project aimed to understand further how genetically identical cells can be primed for differentiation and …
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Callus Development and Organogenesis in Cultured Explants of Cowpea (Vigna unguiculata (L.) Walp
Cowpea, Vigna unguiculata (L.) Walp is an excellent source of protein, vitamins and minerals and a major food crop many parts of Africa. Optimal production levels are hampered by insect pests and diseases. Biotechnological techniques such as tissue culture and genetic engineering can aid in the …
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TET1 AND TRANSCRIPTION FACTOR REGULATION OF LINEAGE SPECIFICATION DURING MOUSE GASTRULATION AND EARLY ORGANOGENESIS
Gastrulation and early organogenesis are overlapping events between Embryonic day (E) 6.25 and E9.5 in mouse that involve the specification of pluripotent cells into the lineage- and tissue-specific precursors of the adult organism. The dozens of cell types that arise during this period are defined …
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Early liver formation in zebrafish: a molecular and morphological approach
… for mutants displaying defects in endodermal organogenesis. Initial analysis of both lines revealed a hypoplastic liver at 48 hpf, and in addition distinct defects in pancreas formation. Positional cloning of the s436 line identified a novel allele of histone deacetylase 1 (hdac1), which plays …
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Development of in vitro regeneration and gene transfer systems for conifer species
… in vitro-grown needles of S. sempervirens, shoot organogenesis and somatic embryogenesis were induced. The influence of genotype and various cytokinins (BA, BPA, and TDZ) in combination with 2,4-D were investigated. Among the cytokinins tested, 20 $\mu$M BPA with 5 $\mu$M 2,4-D produced the …
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Mesoderm diversification during mouse embryonic development
… and molecular level. Gastrulation and early organogenesis are two of the most critical events during these early stages, when pluripotent cells, able to generate any cell in the embryo, proliferate and become lineage-restricted into the progenitors of the major organs. The vast amount of cell …
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Regeneration and genetic transformation of rose and evergreen azalea
… and highly reliable regeneration systems via organogenesis and/or somatic embryogenesis, and develop gene transfer systems for these two important floral crops.
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Model for tooth development in vitro
… the recapitulation of critical initial steps of organogenesis in vitro, is more expedient. Identification of key players and basic mechanisms behind organ formation is one of the major challenges for tissue engineering. Developmental biology addresses these questions and much knowledge has been …
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Function of two closely related fibroblast growth factors in early mesoderm development of <em>Drosophila melanogaster</em>
… gastrulation and mesoderm differentiation during organogenesis, loss and gain of function studies were performed. In an approach of functional analysis, a single mutant allele of ths was generated, ths759, for comparison of the single mutant conditions of ths and the null mesodermal cells to …
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