Global ETD Search
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Showing 1 to 4 of 4 for “"organic anion transport"”.
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Functional and Molecular Aspects of Xenobiotic Transport in Choroid Plexus
… brain. The CP not only secretes CSF, but also transports potentially toxic xenobiotics and waste products of neural metabolism to the blood for eventual clearance in kidney and liver. For several decades it has been known that the CP is actively involved in removing organic anions and other …
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Transport von Paraaminohippursäure, Furosemid, Hydrochlorothiazid, Cimetidin, 11-Deoxycorticosteron und Taurocholat an der basolateralen Membran proximaler Nierentubuli
The renal basolateral transport system is an efficient system for secretion of a wide range of different drugs. One important part of this system is the organic anion transport system (OATS1), which is known for its wide range of substrate-specifity. Previous studies could demonstrate the …
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Characterization of a human renal organic anion transporter
The renal excretion of organic anions, including a variety of endogenous substances, xenobiotics and their metabolites, involves an organic anion transport system with multiple specificity. The well characterized basolateral uptake step of this process involves the organic anion transporter 1 …
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Cloning and characterization of organic anion systems in the adrenal cortex and their role in steroid release
… and medicine. Previous studies have suggested transporter(s) may participate in this process. In this study the characteristic features of the previously demonstrated ROAT1-like exchange transport system in bovine adrenal cells were investigated with representative substrates. Corticotrophin …