Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"organ transplant"”.
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Improving Awareness of Skin Cancer in Organ Transplant Recipients of Color
Organ transplant recipients are at high risk for skin cancer. Currently, more than half of the transplant waiting list is composed of skin of color patients. Skin cancer in skin of color is associated with higher morbidity and mortality and has a different clinical presentation and risk factors. …
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Specialized Transplant Orientation: Improving Nursing Competence Caring for the Solid Organ Transplant Patient
… from 12 patients to >20. The number of solid organ transplants has also grown annually, from 82 in 2013 to 102 in 2014, with that number quickly being exceeded in 2015. Year to date there have been 30 new hires to the unit, most without previous PICU or transplant experience. Education needs …
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Association Between Posttraumatic Growth, Medication Adherence, and Barriers to Adherence in Pediatric Solid Organ Transplant Patients and Their Caregivers
… Little is known about PTG in pediatric solid organ transplant (SOT) patients and their caregivers or PTG's relationship with health behaviors. Study aims were to longitudinally evaluate 1) the role of medication nonadherence and BTA on PTG, and 2) PTG's influence on medication nonadherence and …
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The gift of life: an existential phenomenological exploration of receiving a lifesaving organ transplant and how this affects life subsequently
At present, there is little research conducted on organ transplantation from the perspective of the organ recipient. This study aimed to explore the experience of undergoing lifesaving organ transplantation and how this may affect life subsequently. For the purpose of this research, lifesaving …
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Tissue Blood Flow and Oxygen Consumption Measured With Near -Infrared Frequency -Domain Spectroscopy
… under intensive care, or undergoing surgery, organ transplant or other interventions.
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Quality Management: A Global Case Study in Organ Transplantation
… US and European countries face an epidemic of organ failure from a multitude of reasons: cancer, genetic predisposition, exposure to harmful chemicals in home or surrounding areas or through drinking, drugs and smoking. Another problem faced, is the ratio of organ donors to organ recipients. …
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Organ Donation in the United States
Introduction: The demand for donor organs far exceeds the number of donors. Approximately 18 people in the United States die every day waiting for an organ transplant. The purpose of this capstone is to describe the demographic characteristics of organ donors, recipients and waitlist populations in …
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Analysis of cytomegalovirus UL97 drug resistance mutations in patients receiving Ganciclovir
… literature, particularly in the post-transplant setting. However, a genotypic assay to detect CMV drug resistance is not available in South Africa and the prevalence of these mutations is therefore unknown. We aimed to document the prevalence and types of CMV UL97 mutations following …
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Novel protocols to induce tolerance to solid organ transplants
… abrogate inflammation in settings such as solid organ transplant rejection or in autoimmune diseases such as systemic lupus erythematosus (SLE). In this thesis, we present data pertaining to three different approaches for targeting DC activation including 1) the use of ethyl p
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Overcoming religious and cultural obstacles to organ donation : a rights-based approach
The transplantation of human tissue, cells and organs has saved and improved the lives of hundreds of thousands of individuals who suffer from organ failure. Advancements in organ transplant technologies have resulted in an increased demand for viable organs for transplantation - a demand which …
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Menstruation and Contraception Patterns of Female Adolescent Transplant Patients
… by collecting information from adolescent female transplant patients who are on mycophenolate mofetil and their guardians within our free-standing children’s hospital. The study surveyed these patients and their caregivers in order to elucidate adolescent girl’s contraceptive knowledge and …
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Design, synthesis, and evaluation of release kinetics of novel LFA-1 and TLR-4 inhibitor prodrugs for localized immunomodulation.
Each year, thousands of organ transplant recipients experience graft rejection due to acute immune responses of the innate and adaptive immune systems. Traditionally, systemic immunosuppression has been used to mitigate these immune responses against the graft, however this can lead to systemic …
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Evaluating the Fungistatic and Fungicidal Activities of Bianthrones as Synthetic Intermediates to Novel Hypericin Analogues.
… to HIV/AIDS, cancer treatments or in the case of organ transplant patients due to the presence of immune suppressants. The research approach adopted in this study includes the synthesis of anthraquinone, anthrone and bianthrones as hypericin derivatives and their effect on yeast by a growth …
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Spectroscopic Technologies and Computational Approaches for Real-Time Detection of FMN as Biomarker during Machine Perfusion
Organ transplant waiting lists are progressively lengthening worldwide due to the shortage of suitable organs, resulting in a high mortality rate among patients. The traditional preservation method is static cold storage, but in recent years a new technique has emerged: machine perfusion. This …
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Sphingolipid synthases of Toxoplasma gondii and other organisms
… individuals - especially AIDS patients, organ transplant recipients and patients receiving anti-cancer chemotherapy. Toxoplasmosis also has economic importance as it results in spontaneous abortion in economically important animals. Due to emerging drug resistance and the possible side …
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The New Normal: A Bourdieusian Examination of Living into Young Adulthood being a Paediatric Heart Transplant Recipient
Improved success of paediatric cardiac transplantation has resulted in increased survival of recipients into young adulthood (19 to 29 years of age). Young adults who received a heart transplant during childhood have experienced multiple life sustaining procedures. As survival and longevity …
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Identification of Novel Regulatory Genes in Acetaminophen Induced Hepatocyte Toxicity by a Genome-Wide CRISPR/Cas9 Screen
… of liver failure, generally resulting in either organ transplant or mortality. The underlying molecular mechanisms of injury are not well understood and effective therapy is limited. Identification of previously unknown genetic risk factors would provide new mechanistic insights and new …
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Nurses' perceptions of clinical competency and individualized care in relation to solid organ transplantation
… study examined nurses’ perceptions of transplant nursing competency (TNC) and individualized care (IC) levels for solid organ transplant (SOT) recipients, living donors, and their families while also exploring the relationships among nurse characteristics, TNC, and IC. Three hundred …
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Transfer Beyond Transplantation: Exploring the Lived Experiences and Embodied Geographies of Organ Recipients
… geographies of individuals who have received an organ transfer. While geographers have long been interested in questions of the body, chronic illness and (dis)ability, and health, there has been limited engagement with the topic of organ transfer and the experience of receiving a new organ(s). …
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Divergent Roles of PI3K and Akt in Rapamycin-induced Cardioprotection against Ischemia-Reperfusion Injury
… stents and in immunosuppresive treatment to organ transplant patients. The mechanism by which this drug protects against I-R injury is currently unknown. The goal of this study is to elucidate rapamycin's cardioprotective signaling pathway. We hypothesized that upregulation of Akt occurs …
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