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Showing 1 to 1 of 1 for “"orexin receptor antagonist"”.
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Effects of Single and Dual Orexin Receptor Antagonists on Trigeminal Nociception
… from primary nociceptors to the hypothalamus. Orexins are excitatory, hypothalamic neuropeptides implicated in pain pathways, as well as regulation of sleep and hunger. More specifically, orexins are involved in trigeminal nerve transmission of migraine pain by modulating neuronal membrane …