Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"orally disintegrating tablets"”.
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Versatility of hot-melt extrusion for dosage form design
… and 25% drug loads) were selected to formulate orally disintegrating tablets (ODTs). ODTs were successfully prepared with excellent friability and rapid disintegration time, in addition to the desired taste-masking effect. In chapter 3, HME was applied to enhance the solubility of class II drugs …
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Implementing process analytical technology (PAT) tools for the analysis and control of manufacturing processes during hot-melt extrusion
… The extruded materials were compressed into orally disintegrating tablets and compared with tablets made using Starlac (as a binder) and the sugar alcohols. Characterization of the tablets showed that there is no significant difference - in terms of weight variation, thickness and hardness - …
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Development of hot-melt extrusion as a novel technique for the formulation of oral solid dosage forms
… The obtained granules were incorporated into orally disintegrating tablets (ODTs). The tablets were developed by varying the ratio of superdisintegrants such as sodium croscarmellose and cross-linked polyvinylpyrrolidone while a direct compression process was used to compress the ODTs under …
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Nanocarriers for drug targeting and improved bioavailability
… - Piroxicam nanosuspensions loaded in oral disintegrating tablet (ODT) for oral delivery - Quercetin nanosuspensions loaded in fast dissolving films for oral delivery The aims of the first work were to improve cutaneous targeting and photostability of tretinoin by using nanosuspension …
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Characterisation of freeze dried amino acids and gelatin based rapidly Disintegrating tablets
Recent research has shown the feasibility of using individual or a combination of amino acids as a replacement component for sugars in RDT formulations. What has emerged from this work is the notion of an optimal concentration of amino acid, i.e. one that is sufficiently high to provide the desired …