Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 40 for “"oral gavage"”.
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Fate and Dissemination of Salmonella Reading in Market-age Turkeys at Processing using Oral Gavage Challenge Model
… Reading (SR) in market-age turkeys using an oral gavage challenge model. One hundred twenty-eight-week-old commercial turkey hens were moved from commercial production to research facilities. Upon arrival, a combination of enrofloxacin, 10 mg/kg, and florfenicol, 20 mg/kg, were orally …
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Effects of Spray-Dried Porcine Plasma (SDPP) Administered as an Oral Gavage on Indicators of Health, Welfare, and Performance in Pigs Transported After Weaning
… or IV. Water + no transport. Pigs received their gavage twice daily for 5 d prior to weaning. Pigs were weaned and either transported or moved directly to the wean-to-finish barn. Rectal temperatures and blood samples were obtained at weaning and after relocation. Body weight was determined on d …
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An Exploratory Study of the Systemic Effects of Lead, Trichloroethylene, and a Mixture of Lead and Trichloroethylene Provided Concurrently by Oral Gavage to Male Rats
Forty rats, in groups of ten, were orally dosed with corn oil, corn oil and 2,000 mg/kg trichloroethylene (TCE), corn oil and 2,000 mg/kg lead carbonate, or a mixture of 2,000 mg/kg each TCE and lead carbonate, in an effort to determine whether or not dual administration of both TCE and lead would …
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The effect of dietary zinc on induction of cytochrome p-450 by phenobarbital or 3-methylcholanthrene in male Sprague-Dawley rats
The effects of dietary (oral) zinc, as zinc chloride, on the hepatic microsomal monooxygenase system in Sprague-Dawley rats was investigated in the present study. Three routes of zinc administration—oral gavage, intraperitoneal injection and dietary supplement—were compared for accumulation of zinc …
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INVESTIGATION OF ACUTE STRESS IMPACT ON NURSERY PIG GASTROINTESTINAL FUNCTION AND ABILITY OF BIOACTIVE COMPONENTS OF GARLIC TO MITIGATE STRESS-INDUCED PHYSIOLOGICAL CHANGES
… were supplemented to pigs and chickens by daily oral gavage for a period of 6 d. The oral gavage of DATS + DATS did not impact nursery pig growth performance, although ileal villus height was increased. Furthermore, there was a linear increase in IL-8 and a decrease in zonula occludens 1 (ZO-1) …
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Flavonol kaempferol in the regulation of glucose homeostasis in diabetes
… kaempferol was administrated once daily via oral gavage to diet-induced obese and insulin-resistant mice or lean STZ-induced diabetic mice. The results demonstrated that long-term oral administration of kaempferol prevents HFD-induced metabolic disorders in middle-aged obese mice. Oral …
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Effect of colostrum supplementation on baby pig performance
… (30 ml). The supplements were given as an oral gavage. A single treatment was administered at 6-h after birth. At 30-h of age approximately 1ml of blood was obtained for an immunocrit assay of serum. The glucose based energy supplement (milk protein, medium chain triglycerides) had no (P > …
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Efficacy of tamoxifen and thymoquinone on tumor development, lipid peroxidation, and total antioxidant capacity in DMBA induced mammary carcinoma in female Sprague-Dawley rats
… tumors were induced by DMBA which was given by oral gavage to four groups: DMBA, DMBA+ TAM, DMBA+ TQ, and DMBA+ TAM & TQ. The control group received tap water only. Starting three weeks later, TAM and/or TQ were administered daily for 10 weeks. Mammary tumors were found in two DMBA treated …
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Suppression of Carcinogenesis and Tumor Progression by an Energy Restriction-Mimetic Agent in Murine Models of Prostate Cancer
… 100 mg/kg/day of OSU-CG5 administered via daily oral gavage suppressed the growth of LNCaP-abl xenograft tumors by 81%. Tumor growth suppression was associated with decreased tumor cell proliferation, as determined by proliferating cell nuclear antigen (PCNA) levels, and modulation of …
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Visualisation of bioluminescent Vibrio midae SY9 K811 in juvenile Haliotis midae abalone using non-invasive bioluminescence imagining
… of the bioluminescent bacterial cells by oral gavage to juvenile Haliotis midae abalone allowed non-invasive visualisation of bioluminescence within abalone for up to 10 hours post-gavage. This study therefore demonstrates the potential for using bioluminescence imaging to investigate the …
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Characterization of VIBRIO Parahaemolyticus-Induced Intestinal Inflammation in the Mouse
… from the cecum and colon of mice infected by oral gavage. Mice infected with a pathogenic, wild type strain of V. parahaemolyticus exhibit intestinal inflammation characterized by epithelial damage, submucosal edema, crypt abscess and hyperplasia, and infiltration of the lamina propria by …
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Gene Expression of the Intestinal Peptide Transporter 1 and Peroxisome Proliferator-Activated Receptor alpha Following Fasting/Refeeding and Ligand Administration in Chickens
… a possible regulatory role for PPARα of PepT1. Oral gavage trials utilizing PPARα ligand WY- 14643 were conducted with layers and broilers. For the layer trial birds were gavaged daily for 3 d with 50 mg WY-14643/kg in carrier (Ligand) or with just carrier (No Ligand) and sampled on d4. For the …
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Do Probiotics Protect Against the Deleterious Effects of a High-Fat Diet?
… fat) diet for 4 weeks while receiving a daily oral gavage of water (C-VSL#3, HF-VSL#3) or probiotics (C+VSL#3, HF+VSL#3) equivalent to 1.2 billion live cultures. Changes in body weight, body composition, respiratory exchange ratio, energy expenditure, and glucose and insulin tolerance were …
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Ranolazine: a Potential Anti-diabetic Drug
… (STZ). Ranolazine was given twice daily via an oral gavage (20 mg/kg) for 5 weeks. blood levels of glucose, insulin, and glycosylated hemoglobin (HbA1c) were measured. Glucose tolerance test was performed in control and treated mice. pancreatic tissues were stained with hematoxylin and eosin or …
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Enhancing Seafood Quality and Safety by Reducing Reliance on Antibiotics: Applying a Novel Antibody in Tilapia
… diet and were challenged via bath immersion or oral gavage with A. hydrophila. Four trials of challenge studies were conducted. Clinical signs of the disease and survival were monitored post-challenge of the bacteria. Out of the 4 trials, one bath immersion trial showed significantly lower …
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Identification of an Interferon Signaling Pathway Linking Membrane Cholesterol Accessibility to Host Defense Against Pathogens
… significantly reduced bacterial burden in an oral gavage model. Furthermore, I found that 25HC blocks L. monocytogenes cell-to-cell spread by attenuating the formation of plasma membrane protrusions. In collaboration with the post-doctoral fellow Kristen Johnson, I have used toxin-based …
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Development of Novel Methods to Study Host-Microbe Interactions In The Larval Zebrafish Gastrointestinal Tract
… alternative to infection via immersion or oral gavage, and replicates the most common route of transmission of gastrointestinal (GI) infection in humans. The foodborne infection assay was then used in combination with enteric nervous system (ENS)-deficient zebrafish, a model for …
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Hydrolysis and Atmospheric Oxidation Reactions of Perfluorinated Carboxylic Acid Precursors
… intestines of rats following a high dose by oral gavage.
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Elucidating the roles of endothelial PTBP1 and PKM2 in Pulmonary Arterial Hypertension: implications for therapy
… of right ventricular systolic pressure following oral gavage TEPP-46 treatment, further supporting the therapeutic potential of PTBP1 and PKM2 inhibition in PAH. Therapeutic benefit was not observed following apigenin treatment, however exploration of alternative routes of delivery and formulation …
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Local exposure and efficacy of a reservoir-based drug delivery device
… than systemic delivery of temozolomide via oral gavage. Local delivery of doxorubicin was not efficacious against either tumor type, and not significantly distinguishable from control groups. Exposure data revealed much higher levels of retained temozolomide across a larger area of brain …
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