Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 69 for “"optical trapping"”.
-
Development of optical trapping assays to investigate bacteriophage T4 packaging
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms
-
Development of a heating stage for an optical trapping microscope
… of biological systems through research using optical tweezers. Currently, experiments involving force and position manipulations of cellular molecules take place at room temperature. Experiments with these molecules have the potential to yield more information about biological systems were …
-
Single-molecule optical trapping studies of the regulation mechanisms of XPD helicase
… Among these powerful interdisciplinary tools, optical tweezers are exceptional. They allow direct, single-molecule manipulation and measurement, fundamentally advancing our understanding of essential cellular processes like molecular motor motion and protein-DNA interactions. This thesis …
-
Experimental methods by optical trapping for investigation of leukocyte cell rolling mechanics
… of a range of experimental methods by optical trapping in order to investigate the mechanical behavior of the leukocyte cell membrane as it undergoes cell rolling. Membrane tethers extracted from the cell during rolling function to slow the cell down and to maintain contact with the …
-
Fresnel-focusing and bessel-beam integrated optical phased arrays for optical trapping applications
Optical trapping and tweezing - the manipulation of particles using optical forces - enables direct interaction with biological samples and non-invasive monitoring of their properties. As such, optical trapping has become a common tool in biology with applications ranging from better understanding …
-
Spatial Emission and Polarization Control in Integrated Photonics for Optical-Trapping and Trapped-Ion Systems
… results in fields including biophotonic optical tweezers and trapped-ion quantum systems. However, the majority of these demonstrations, while offering advantages in size, cost, and dense integration, lag behind their bulk-optic counterparts, limited by a lack of critical advanced …
-
Novel optical trapping - from enhanced forces via vector beams to characterizing optical properties of trapped microparticles
… checksum: 82ec029b346982bddf02073e916eb734 (MD5) OpticalTrapping.tex: 17663 bytes, checksum: d845f91430736d6e098172e4cf2433fb (MD5) References.bib: 7592 bytes, checksum: 19f8daddf98c11859b904eb1a5207695 (MD5) Theory.tex: 30403 bytes, checksum: 5e92f6d396d5c0488ed582d5b38761c1 (MD5)
-
Optical studies of colloidal quantum dots : optical trapping with plasmonic nanoapertures and thermal recovery from photoinduced dimming
… this goal, QDs were introduced into the field of optical trapping. Silica coated QDs were optically trapped using bowtie apertures in a thin silver film with low incident flux of 1.56 MW/cm 2 at 1064 nm. Additionally, QDs emitted upon trapping via two-photon excitation from the trapping laser due …
-
Generation and imaging of structural laser beams for optical trapping of airborne particles and light-matter interaction applications.
Recently emerged non-diffracting optical Bessel-Gaussian beams have extended the `optical toolbox' in laser interaction with matter studies, providing many techniques that are not possible using conventional Gaussian beams. The research work performed under this thesis focuses on the design, …
-
Generation and imaging of structural laser beams for optical trapping of airborne particles and light-matter interaction applications.
Recently emerged non-diffracting optical Bessel-Gaussian beams have extended the `optical toolbox' in laser interaction with matter studies, providing many techniques that are not possible using conventional Gaussian beams. The research work performed under this thesis focuses on the design, …
-
Combined optical trapping and single molecule fluorescence to study the force-dependent binding kinetics between filamentous actin and its partners
… level by using an instrument that combines optical trapping with single molecule fluorescence. The main focus of this work was the design and construction of the experimental equipment. The results show position detection capabilities with a resolution of 5 nm. Also, the trap stiffness …
-
Development of a Novel Gradient-Force Tapered Fibre Optical Tweezers System for 3D Optical Trapping at Near Horizontal Fibre Insertion Angles
The use of optical fibre as a mechanism for the delivery of the trapping laser beam to the sample chamber significantly reduces both the size and the build costs of “Optical Tweezers”. Furthermore, the use of fibre facilitates the decoupling of the optical trapping beam from the microscope optics, …
-
High-Resolution Dynamic Mapping Of Histone-Dna Interactions In A Nucleosome Through The Use And Development Of Novel Optical Trapping Techniques
… to DNA associated with a nucleosome. Two novel optical trapping techniques are described in Chapters 4 and 5, respectively: the adaptation of the unzipping method to apply to new biological assays and a novel microfluidic flow cell compatible with single molecule optical trapping experiments. …
-
Antibody-Antigen assay design for combined optical tweezers and fluorescence
The recent development in combined optical trapping and fluorescence technology promises to enable unbindinig force studies of receptor-ligand interactions, whose specificity play a crucial role in the function of many biological systems. This thesis focuses on the development of assay designs for …
-
Modeling and Experimental Techniques to Demonstrate Nanomanipulation With Optical Tweezers
… of effective prototyping tools at the nanoscale. Optical trapping is well established for flexible three-dimensional manipulation of components at the microscale. However, it has so far not been demonstrated to confine nanoparticles, for long enough time to be useful in nanoassembly applications. …
-
Confinement and Tracking of Brownian Particles in a Bessel Beam Standing Wave
Optical trapping is a useful tool for manipulating microscopic particles and probing the physical interactions of matter. However, previous optical trapping techniques introduced complications for analyzing Brownian particle diffusion in viscous media because they either restricted the particles' …
-
Learning-Based Control for Optically Trapped Non-Spherical Particles
… size is on the micron-scale or smaller. An optical tweezers system harnesses the momentum of light to manipulate these small particles by trapping them near the focal point of a sharply focused laser beam. Since the inception of optical trapping in 1986, it has enabled many scientific …
-
Dynamic behavior of healthy and malaria infected human red blood cells
… characterizations using advanced optical trapping techniques and (2) microfluidic flow experiments. A new set of dynamic optical trapping experiments are developed using an alternate loading configuration and a broader range of deformation rates (up to 100ptm/s) and forcing …
-
Development of a plasmon resonance enhanced optical trap for characterisation of single metal nanoparticle
… a plasmon resonance based gold nanorod trapping platform and suggest methods for characterizing a trapped single nanoparticle. While there are published methods that emphasize on building up an optical trapping setup or trap single gold nanorod using high power lasers, none were found …
-
Design of a dual beam optical trap
Dual beam optical traps use radiation pressure from two counterpropagating laser beams to manipulate microscopic particles. Typical traps use optical fibers to guide those beams. This thesis proposes a design for the coaxial alignment of optical fibers that allows for the fibers to translate along …
Page 1 of 4