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Showing 1 to 17 of 17 for “"optical biosensors"”.
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Numerical characterisation of label free optical biosensors
… methods to simulate advance and complex optical biosensor structures. Finite Element Method (FEM) has been established as one of the most powerful and versatile numerical method and has been implemented in this thesis to characterize, analyse and optimise label-free optical biosensors for …
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Design, fabrication and characterization of resonant waveguide grating based optical biosensors
… home based point-of-care diagnostics. Label-free optical biosensing with high sensitivity, throughput, compactness, and low cost, plays an important role to resolve these diagnostic challenges and pushes the detection limit down to single molecule. Optical nanostructures, specifically the resonant …
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Study and development of label-free optical biosensors for biomedical applications
… mentioned above, the study and development of optical label-free sensor technologies have been undertaken here. In general, label-free photonic crystal (PC) biosensors and metal nanodome array surface-enhanced Raman scattering (SERS) substrates, both of which are fabricated by nanoreplica …
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Elastomeric grating sensor for multifunctional optofluidic biosensing
Optical sensing techniques are being employed in widespread applications ranging from aerospace to electronics, process control and medicine. Optical biosensors are desirable in various clinical applications for their greater sensitivity, electrical passivity, wide dynamic range and high spatial …
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SURFACE PLASMON RESONANCE IMAGING BIOSENSORS FOR THE DETECTION OF PATHOGENS AND TOXINS IN FOOD
… good selectivity and sensitivity. In particular, optical biosensors based on Surface Plasmon Resonance Imaging (SPRI) are attractive because they allow the sensitive detection of analytes from food matrices in real-time. SPRI can assays crude samples without purification and can exploits …
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Modeling and simulation of silicon photonics based optical ring resonator biosensor
… because these devices use silicon as the optical medium that can be fabricated using the standard CMOS technology. A biosensor is an analytical device used for the identification of an analyte that conglomerates a vital element with a physicochemical indicator. Optical biosensors are …
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Carbon nanotube-based sensors for label-free protein detection
Optical biosensors based on fluorescent single-walled carbon nanotubes (SWNT) are a promising alternative to conventional biosensors due to the exceptional photophysical properties of SWNT. Such sensors can enable highly-sensitive, selective, and real-time detection of biological analytes. However, …
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Early Diagnosis of Alzheimer's Disease and Studying Binding to Opioid Receptors using Whispering Gallery Mode Microtoroid Biosensors
… quality factor, whispering gallery mode (WGM) optical biosensors offer several advantages over other biosensors including higher sensitivity and label-free capability. At the resonance condition, light circulates within the perimeter of the WGM resonator by total internal reflection and …
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Towards efficient three-dimensional wide-angle beam propagation methods and theoretical study of nanostructures for enhanced performance of photonic devices
… carried out the study of improved performance of optical devices such as label-free optical biosensors, light-emitting diodes and solar cells by means of numerical and analytical methods. We have proposed a solution for enhanced sensitivity of a silicon-on-insulator surface plasmon interference …
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Photonic Crystals For Optofluidic Transport, Trapping And Biosensing
… interest to the optics community. Their unique optical properties have revolutionized the field of photonics and have enabled a new class of optical devices with applications in a broad range of areas such as creating nanophotonic light guiding circuits, efficient optical add-drop filters and …
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Construction and Performance Optimization of Bioconjugated Nanosensors for Early Detection of Breast Cancer and Pro-inflammatory Diseases
… Single-walled carbon nanotube (SWCNT) based optical nanosensors have notably garnered interest due to the unique characteristics of their near-infrared fluorescence emission, including tissue transparency, photostability, and various chiralities with discrete absorption and fluorescence …
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Sensitive microarray-based biomarker detection using photonic crystal enhanced fluorescence and label-free imaging
… diversity. While there exist reports on novel optical and electrochemical approaches capable of detection biomarkers at concentrations in the subpicomolar range, currently no platforms for the multiplexed cancer biomarker detection are in widespread use in point-of-care (POC) settings. This …
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Design and investigation of a novel 𝝿-configuration spr sensor for multi-parameter biosensing applications.
… early detection in complex biological matrices. Optical biosensors based on Surface Plasmon Resonance (SPR) principles have emerged as a viable alternative, allowing for real-time, label-free molecular interaction monitoring. However, widespread adoption of conventional SPR platforms has been …
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Development of silicon photonic microring resonator biosensors for multiplexed cytokine assays and in vitro diagnostics
… photonic microring resonators, a class of high-Q optical sensors, represent a promising platform for rapid, multiparameter in vitro measurements. The original device design utilizes 32-ring arrays for real-time biomolecular sensing without fluorescent labels, and these optical biosensors display …
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A systematic study of ion-induced nanopatterning on photonic crystal-based label-free optical biosensor
Photonic crystal (PC)-based biosensors are promising candidates for label-based fluorescence and label-free optical biosensors. This is due to the presence of PC, a periodically-structured dielectric material with diffraction gratings engineered on the surface that can control light propagation …
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Ionic Self-Assembled Multilayers in a Long Period Grating Sensor for Bacteria and as a Source of Second-Harmonic Generation Plasmonically Enhanced by Silver Nanoprisms
… generation (SHG). SHG is a nonlinear optical process in which light is instantaneously converted to half its wavelength in the presence of intense electric fields. Localized surface plasmons (LSPs) in metal nanoparticles produce strong electric field enhancements, especially at sharp …