Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 118 for “"opioid use"”.
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Predictors of prolonged opioid use following lumbar fusion
… 2.4 times between 1998 and 2008.2 Rates of opioid pain reliever (OPR) use at 24 months post-lumbar fusion have been reported in up to 30% to 67% of patients. Currently, the number of OPR-related deaths in the US exceeds deaths from motor vehicle accidents.3 The objective of this study is to …
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Opioid use and abuse in the United States
<p>Opioids have quadrupled the number of unintentional drug overdose deaths since 1999 and are now among the leading causes of death in the United States. Though some reform has recently occurred, the United States continues to operate largely under a punitive criminal justice model despite …
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The Social Organization of Opioid Use for Chronic Pain
… ethnography of the social organization of opioid use for chronic pain management in Ontario, Canada. Within the context of the contemporary ‘opioid crisis,’ people with chronic pain have found their access to prescription opioids restricted as physicians rapidly taper patients’ doses, adopt …
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Molecular Mechanisms of Opioid Use Disorder in Human Brain Models
<p>Opioid use disorder (OUD) is a national and global public health crisis with no end in sight. While studies from animal models hint at widespread epigenetic and transcriptomic alterations of opioid drugs, the molecular consequences of long-term exposure to opioid drugs in human brain is still …
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Opioid use, dependence and complications following musculoskeletal trauma and surgery
Long-term opioid use for chronic non-cancer pain has increased substantially. An increasing body of evidence is indicating that there has been an overestimation of benefit and an underestimation of harms, yet rates of use and dependence are not well quantified. The aims were to explore the …
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Improving prediction of opioid use disorder with machine learning algorithms
Opioid Use Disorder (OUD) refers to a concerning pattern of opioid use that results in considerable impairment or distress. It is a chronic and treatable condition that can impact individuals irrespective of their race, gender, income, or social standing. Therefore, accurately predicting …
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Counseling interventions with buprenorphine for treatment of opioid use disorders
Opioid abuse and opioid related deaths continue to affect families and communities across the United States. Medication-assisted treatment shows advantages over other types of interventions for opioid use disorder (OUD) (Bart, 2012). While buprenorphine, an approved medication for the treatment of …
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Reducing Opioid Use Following Posterior Spinal Fusion Procedures: A Pilot Project
<p>Importance: Opioid misuse and mortality remain a prevalent problem in the United States and there is a high rate of chronic opioid-use after spinal fusions. Current guidelines recommend the optimization of non-opioid analgesics as a primary pain control strategy with opioids acting as a …
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Identification and treatment of opioid use disorder in the emergency department
Background: Opioid Use Disorder (OUD) is a common comorbidity in emergency department (ED) settings. This study aimed to introduce a standard of care that incorporates medication-assisted treatment and facilitates referrals for continuous therapy among individuals with OUD seeking assistance in the …
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Barriers and Facilitators to Opioid Use Treatment and Recovery Services During Pregnancy
… identify barriers and facilitators to opioid use treatment and recovery services among pregnant and nonpregnant women who misuse opioids.<strong> </strong></p> <p><strong>Background: </strong>Over 130 Americans die daily after overdosing on opioids. Women have not been immune from …
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The Impact of Pain on Key Outcomes in Opioid Use Disorder Recovery
Opioid misuse and addiction constitute a significant public health challenge in the 21st century, with opioids involved in the majority of drug overdose deaths since 1999. A vigorously researched area that contributes substantially to the opioid misuse and addiction challenge is pain. The impact of …
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Pre-treatment Level of Opioid Use as a Predictor of Chronic Pain Rehabilitation Outcome
… examines the relationship between pre-treatment opioid use and treatment outcomes among 1,226 chronic pain patients who participated in a functional restoration program. Patients were divided into five categories based on self-reported pre-treatment level of opioid use. Patients received an …
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Responsibility and Resistance at the Clinic – How is Opioid Use Now Understood and Managed?
Post-industrialisation, opioid use has been problematised to serve various socio-political interests. This thesis explores how medical institutions now manage what is increasingly described as an international opioid ‘crisis’. Through an institutional ethnography of an opioid substitution treatment …
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Epigenetics and biopolitics: moving away from using punitive policies to address opioid use in pregnancy
Opioid use in pregnancy is the latest in a long list of social issues in the United States that is being addressed with punitive policies that disproportionately affect women of color and their families and do not focus on environmental factors contributing to increasing drug use in pregnancy. …
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Opioid Use after Transforaminal Lumbar Interbody Fusion: A Comparison between Open and Minimally Invasive Surgery
Background: Opioids are medications frequently used in patients with moderate and severe chronic pain. Their pharmacologic profile allows their use in acute severe postoperative pain. However, due to their highly addictive profile, opioid misuse is considered a public health issue. Vertebral spine …
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The Impact of Neighbourhood-Level Marginalization on risk of Opioid Overdose and Opioid Use Disorder
Background: Canada is in the midst of an opioid crisis, characterized by a dramatic increase in opioid-related poisonings, deaths, and dependency over the course of several years. Neighbourhood-level marginalization, defined as the degree to which individuals living within a neighbourhood are …
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Complexities and comorbidities in patients with chronic non-cancer pain: Suicidal behaviours and pharmaceutical opioid use
… with suicidality, the nature of pharmaceutical opioid use in people living with CNCP, the prevalence of Borderline Personality Disorder (BPD) in people living with CNCP, and associations between suicidality (i.e. ideation, plans and attempts) and problematic opioid use (e.g. dependence) in this …
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MEDICAL CANNABIS USE AMONG CHRONIC PAIN PATIENTS AND ASSOCIATIONS WITH PRESCRIPTION OPIOID USE: A RETROSPECTIVE STUDY
<p>Medical cannabis is increasingly used as a treatment for chronic pain, and there is initial evidence that medical cannabis may lead to a subsequent decrease in prescription opioid use. The objective of the current study was to conduct a retrospective, naturalistic examination of medical cannabis …
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A Mixed Methods Exploration Of Stigma, Discrimination, And Sleep Among Those On Medication For Opioid Use Disorder
… occurs in as many as 75% of people with Opioid Use Disorder (OUD). The prevalence of insomnia is attributable to concurrent factors such as mental health disorders, chronic pain, and medication use; however the contribution of social factors is not well understood. Persistent social …
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Come as You Are: The Acceptability of Harm Reduction Approaches for Opioid Use Disorder among Professional Counselors
Over the last two decades, the Opioid Epidemic has caused immense harm to communities nationwide. Over 400,000 fatal opioid overdoses occurred in the United States between 1999 and 2017 (CDC, 2019). Professional counselors are among the front-line treatment providers addressing substance use, …
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