Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"opioid overdose"”.
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Preventing Opioid Overdose: From Prediction to Operationalization
The opioid epidemic remains a significant public health challenge in the US. A potential catalyst for reducing the incidence of opioid-related harm is the development and operationalization of risk stratification models. Prior work has focused on the statistical performance of such models without …
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Engineering a microneedle patch for opioid overdose therapy
The opioid overdose epidemic, exacerbated by potent synthetic opioids such as fentanyl, presents a critical challenge to public health. Naloxone hydrochloride, a μ-opioid receptor antagonist, is the frontline therapeutic for overdose reversal; however, its clinical utility is constrained by rapid …
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Opioid overdose trends in children, adolescents and young adults
Introduction: The opioid epidemic has become a major public health problem in the United States, reaching record high mortality rates during the pandemic. While trends have been documented in adults, there is a need to examine these patterns among younger populations. Aim: This study analyzes …
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Reducing opioid overdose-related deaths in Michigan : a policy analysis
Currently, the opioid epidemic is spreading across the United States (U.S.) leaving individuals, families, and communities fractured. According to the Centers for Disease Control and Prevention (CDC) (2020) opioid overdose is the leading cause of mortality and disability among people with opioid …
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The Grieving Process of Opioid Overdose Bereaved Parents in Maryland
In recent years, the opioid epidemic in the United States has garnered attention on a federal and local level due to the increasing number of fatal overdoses. This study aimed to explore the experiences of parents who have an adult child who has passed away from an opioid overdose. This study used …
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Chronic Pain and The Prescription Opioid Overdose Epidemic: Addressing Provider Attitudes and Concerns
… control have led to an epidemic of prescription opioid related overdose deaths. Primary care providers manage the majority of chronic pain patients in the United States but the care provided is highly variable and often a source of frustration for providers and patients. The purpose of this …
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The Impact of Neighbourhood-Level Marginalization on risk of Opioid Overdose and Opioid Use Disorder
Background: Canada is in the midst of an opioid crisis, characterized by a dramatic increase in opioid-related poisonings, deaths, and dependency over the course of several years. Neighbourhood-level marginalization, defined as the degree to which individuals living within a neighbourhood are …
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THE HIDDEN HAUNTINGS OF THE OPIOID & OVERDOSE CRISIS: A POLICY REVIEW OF HARM REDUCTION AND SAFE INJECTION SITES IN VANCOUVER, OTTAWA, TORONTO, LONDON, AND WINDSOR.
The drug and opioid overdose crisis have led to the death of hundreds of thousands of people. As such, harm reduction and safe injection sites have been making their appearances throughout Canada, specifically within British Columbia and Ontario. The policies held in Vancouver, Ottawa, Toronto, …
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Intranasal Naloxone Adminstration Education
… and members of their social network. Fatal opioid overdose rates from prescribed or illicit opioids are four times greater in Lake County than California. The setting is Lake County, California, with a population of 65, 000, a radius of 1,300 square miles, and an annual per capita income of …
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A Geographic Framework for the Optimal Placement of Interventions for Opioid Treatment Deployment in Underserved Areas (OPIOID-UA)
… care system delivers care,; the crisis is the opioid overdose epidemic. The opioid overdose crisis in the United States (US) is well documented as overdose mortality has continued to climb year after year, is a leading cause of accidental death, and has contributed to a reduced life expectancy. …
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The creation, validation, and implementation of five deprivation indices for the five healthy people 2030 domains
… Indices (HP 2030 DI) were implemented to predict opioid overdose deaths, naloxone saturation, and addiction perception better than standard deprivation indices. The results of the opioid overdose indicated the HP 2030 DI scores could not predict overdose but neither could the other deprivation …
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The economics of pain management
… of public policies that reduce availability of opioid pain relievers. In each of the three chapters, I exploit state-level variation in the introduction of Prescription Monitoring Program (PMP) laws as a source of plausibly exogenous variation in availability of prescription opioids. I employ …
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A Multi-Level Analysis of Major Health Challenges in the United States Using Data Analytics Approaches
… and quality of healthcare. Infant mortality, opioid overdose death, and hospital readmission after stroke are some of these important public health concerns that can impact the effectiveness and outcomes of the healthcare system. We analyze these problems through the industrial engineering and …
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HEALTH EQUITY IN PAIN MANAGMENT DURING THE OPIOID EPIDEMIC: HOW STEREOTYPES, RACISM, BIAS HARM VULNERABLE POPULATIONS
… have demonstrated bias when prescribing opioids to Black, Indigenous, and people of color (BIPOC) populations. These patients deserve proper pain control. In 2021, the CDC stated 75,673 people died in the United States from opioid overdose. Because of this, the medical community has an …
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An Ethical Analysis of Safe Supply
Opioid overdose deaths in the United States have been steadily increasing for decades. Initially, these deaths were driven by overdoses from prescription opioids. Strict limits were placed on opioid prescriptions to decrease the supply of available opioids. Instead, this prompted a shift toward the …
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Visualizing global drug flows : transnational connections to the overdose crisis in New England, USA
… fentanyl (IMF), a powerful synthetic opioid; and (b) naloxone, an opioid overdose antidote used in the public health crisis of drug overdose deaths in Massachusetts, USA. Beginning locally in Massachusetts, I filmed parents reflecting on losing children to overdoses, first responders …
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Changes in Self-Concept and Substance-Related Cognitions During Short-Term Residential Substance Use Treatment
The United States is in the midst of an opioid crisis, with more than 130 people dying each day from an opioid overdose (Centers for Disease Control and Prevention [CDC], 2018a). Given the recent spike in overdose deaths associated with highly potent synthetic opioids (i.e., fentanyl), there are …
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The development and use of cutting edge next generation sequencing methodologies to study RNA viruses
… we wanted to look at the brain as well. As opioid overdose deaths have increased in recently in the U.S. (coinciding with the COVID-19 pandemic) we investigated the potential impact of opioid use on severity of neurological disease from RNA virus infection, looking at expression of genes …
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Come as You Are: The Acceptability of Harm Reduction Approaches for Opioid Use Disorder among Professional Counselors
Over the last two decades, the Opioid Epidemic has caused immense harm to communities nationwide. Over 400,000 fatal opioid overdoses occurred in the United States between 1999 and 2017 (CDC, 2019). Professional counselors are among the front-line treatment providers addressing substance use, …
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People with active opioid use disorder as first responders to opioid overdoses: Improving implementation intentions to administer naloxone
The ongoing opioid crisis presents a significant public health challenge particularly for people who use opioids (PWUO). Naloxone is an opioid antagonist crucial to reducing opioid overdose mortality. Inconsistencies exist among PWUO in obtaining, carrying, discussing, and administering naloxone. …
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