Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"opioid efficacy"”.
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PHARMACOGENOMICS OF OPIOID RESPONSE IN EUROPEAN ADVANCED CANCER PATIENTS
Background: Strong opioids, which are drugs in the third step of the World Health Organization’s analgesic ladder, are the standard of care for treating pain in advanced cancer patients. Unfortunately, a significant minority of them do not benefit from analgesic therapy, or experience several side …
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EFFECTS OF MU OPIOID RECEPTOR AGONISTS ON INTRACRANIAL SELF-STIMULATION IN THE ABSENCE AND PRESENCE OF “PAIN” IN RATS
Pain is a significant health problem. Mu opioid receptor agonists are used clinically as analgesics, but their use is constrained by high abuse liability. Intracranial self-stimulation (ICSS) is a preclinical behavioral procedure that has been used to assess abuse potential of opioids, and …