Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"operant responding"”.
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Motivational State-Dependent Renewal of Operant Responding under Food and Water Deprivation States
… reinstatement are two different ways in which operant responding may recover following extinction. These and other forms of recovery following extinction have been described as relapse phenomena and demonstrate the context-specific nature of extinction learning. Most studies of relapse …
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Experimental Analysis of Operant Learning with Social Reinforcement in Mice
… reinforcement/reward (SR) procedures in which operant responses are reinforced by the opportunity to interact in some way with other members of the same species (conspecifics) have been developed to study operant social learning in nonhuman animals, particularly with rats. Interest and research …
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Neuromedin U Acts via the Paraventricular Nucleus of the Hypothalamus and the Dorsal Raphe Nucleus to Regulate Motivation for High-Fat Food
… reinforcers. Here, we used a progressive-ratio operant responding paradigm in combination with assessments of food intake, craving-like behavior, and locomotor activity to evaluate the effects of NMU in rats, and identify the brain regions mediating these effects. We found that peripheral …
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Effects of selective neurotensin receptor antagonists on responding for brain stimulation reward
… animals can easily be trained to produce an operant response to obtain such a stimulation. Previous studies have shown that the rewarding effect of mesencephalic electrical stimulation is potentiated by intracerebroventricular and by ventral mesencephalic microinjections of neurotensin (NT); …
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Role of the Subthalamic Nucleus in the Circuitry Mediating Food- and Cocaine-Seeking Behavior
… we assess the effects of STN lesions on operant responding for reward under a progressive ratio (PR) schedule of reinforcement, a schedule thought to measure the reinforcing efficacy of rewards. Bilateral STN lesions enhance responding for sucrose reward, but attenuate responding for …
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An Examination of Affective Blunting in Rodents
… between treatment groups found in female operant responding, nor in the sucrose preference test. This study is the first known attempt to exhibit affective blunting in an animal model.</p>
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Within-session session changes in responding as a function of habituation vs. satiation.
… here sought to determine whether decreases in operant responding by 3 adults with developmental disabilities were due to satiation or habituation. During baseline, participants placed poker chips into a container, and no reinforcement was available. Within subsequent phases, participants …
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Ethanol priming and its effects on consumption and accumbal plasticity
… shell, which encode different aspects of drug responding and have distinct dopamine responses. The accumbens can be further divided into two subpopulations of D1-dopamine receptor (D1) or D2-dopamine receptor (D2) expressing medium spiny neurons (MSNs) that precipitate different intracellular …
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Dopamine and reward : effects of dopamine antagonist drugs on operant and consummatory behaviours
… reinforcement. Within-session decrements in both operant and consummatory behaviour were observed following administration of sulpiride to the anterodorsal striatum, but not following administration of sulpiride to the nucleus accumbens. The implications of this finding are discussed in relation …
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Dissociating Roles for the Nucleus Accumbens Core and Shell in Priming-, Cue-, and Stress-Induced Reinstatement of Food-Seeking Behavior
… model, and research has found that this operant responding behavior for rewards is differentially affected by manipulation of the nucleus accumbens subregions, the core and shell. To determine if the nucleus accumbens core and shell uniquely contribute to the reinstatement of …
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Neuroimmune and Developmental Mechanisms Regulating Motivational Behaviors for Opioids
… neither handling nor pDNA-IL-10 treatment alters operant responding for food or sucrose rewards. These results help define the conditions under which ventral striatal neuroimmune signaling may influence motivated behaviors for highly reinforcing opioid drugs.</p>
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The Effect of Typical and Atypical Antipsychotics on the MK-801 Induced Deficit in Behavioural Inhibition
… measured as the lack of extinction during operant procedures. As such, MK-801 has the potential to be used as a preclinical animal model of cognitive deficits that arise in schizophrenia. The present thesis sought to explore if typical and/or atypical antipsychotics have the ability to …
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Discriminative stimulus properties of 3-substituent rimonabant analogs
… effects in humans are likely to produce THC-like operant responding in animals trained to discriminate between the interoceptive stimuli produced by THC relative to vehicle. O-6629 and O-6658 decreased locomotor activity and body temperature and produced catalepsy. O-6629, but not O-6658 produced …
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Achieving pharmacologically relevant IV alcohol self-administration in the rat
… of the dark cycle. Once animals achieved stable operant responding on both levers for an orally delivered 1% sucrose solution (1S) on a FR4 schedule, surgery was conducted to implant an indwelling jugular catheter. Animals were habituated to the attachment of infusion apparatus and received twice …
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Studio degli effetti della pre-esposizione adolescenziale al Δ9-THC nell’autosomministrazione di eroina, in età adulta, in un modello animale di maggiore (ratti Lewis) e minore (ratti Fischer 344) predisposizione all’abuso.
… Ratio-1 (FR-1) (1NP = 1 infusion) schedule of responding. When criterion of acquisition was met, LEW and F344 rats were subjected to self administer heroin: i) under Fixed Ratio (FR-3 and FR-5) schedule of responding (Exp I), to better understand how Δ9-THC could influence heroin reinforcing …
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Cannabinoid Modulation of Reinforcement Maintained by Stimulation of the Medial Forebrain Bundle in C57Bl/6J Mice
… such as psychomotor stimulants, facilitate responding for ICSS. While a few studies have shown facilitating effects of cannabinoids in rats, several have shown the opposite effect, and no studies so far have evaluated cannabinoids in mouse ICSS. Furthermore there are no studies evaluating …