Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"oncomirs"”.
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MicroRNA Expression Profiling of Multipotent Adult Germline Stem Cells
… Unterschieden in der Expression von einigen Oncomirs, dass undifferenzierte maGSCS und ESCs aus einem 129/Sv Hintergrund sich in ihrem microRNAome kaum unterscheiden. Im Gegensatz dazu unterscheiden sich undifferenzierte maGSCs aus der transgenen Stra8-EGFP-Rosa-Maus von allen anderen …
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Investigating the relationship between miRNA expression and epithelial mesenchymal transition in colorectal cancer
… function as tumour suppressors or oncogenes (oncomirs). Tumour suppressor miRNAs reverse EMT while oncomirs activate it. Therefore, investigating the relationship between miRNAs and EMT is important in addressing metastasis of colorectal cancers (CRC). Aims and Objectives: The aim of the study …
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microRNA expression profile of undifferentiated and differentiating pluripotent cells
… gehören zu der so genannten miRNA-Gruppe der Oncomirs . Diese Gruppe besteht aus den Mitgliedern des miR-17-92 Clusters und seiner Paralogen. Exprimierung von typischen Mitgliedern des miR-17-92 Cluster (miR-17, miR-19b, mir-20a, miR-20b) wurde folglich mittels qRT-PCR in ESCs und maGSCs …
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RESVERATROL INHIBITS PROSTATE CANCER GROWTH AND METASTASIS BY TARGETING AKT/MICRORNA-21 PATHWAY
… level. Some miRNAs has been termed as oncomirs due to their role in promoting tumor growth, invasion and metastasis. One such oncomir is <italic>microRNA-21</italic> (<italic>miR-21</italic>) whose levels are often up-regulated in a number of cancers, including prostate cancer. …
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RNA Interference and cyclooxygenase-2 (COX-2) regulation in colon cancer cells
… that some miRNAs work as tumor suppressors or oncomiRs in colon cancer. Thus, my hypothesis was that overexpressed COX-2 protein in colon cancer could be the result of decreased levels of one or more tumor suppressor miRNAs. In this thesis, I clearly show an inverse correlation between COX-2 …