Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"ompA"”.
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Rendimiento de diferentes métodos de PCR en el diagnóstico molecular de las rickettsiosis humanas transmitidas por garrapatas
… que amplifican los genes ADNr 16S, htrA, gltA, ompA y ompB para el diagnóstico molecular de rickettsiosis. Para ello estudiamos 72 muestras (sangre con EDTA, biopsias de piel y garrapatas) de 52 pacientes con rickettsiosis en fase aguda y confimada por PCR. Se realizaron PCRs sencillas [ADNr …
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THE ROLE OF OUTER MEMBRANE PROTEIN A IN ANAPLASMA MARGINALE CELLULAR INVASION AND ITS POTENTIAL AS A CROSS-PROTECTIVE ANTIGEN
… A. phagocytophilum outer membrane protein A (ApOmpA) as being critical for cellular invasion and is expressed during infection of mammalian but not tick cells. Disrupting ApOmpA-host cell interactions significantly inhibits A. phagocytophilum entry into host cells. ApOmpA and its A. marginale …
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Bakteriofago vB_EcoS_NBD2 kilmės nanovamzdelių pritaikymas baltyminių fragmentų eksponavimui /
… for the presentation of outer membrane protein OmpA fragments of opportunistic pathogen Acinetobacter baumannii. Since there is no vaccine against multi-drug resistant A. baumannii, chimeric nanotubes displaying OmpA protein fragments have a potential application to be used as an immunogenic …
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Chlamydia trachomatis diversity and pathogenesis in young South African women, related to HPV prevalence and risk
… women experiencing higher rates of infection compared to men. Due to these often being asymptomatic, both CT and HPV infections are challenging to detect in the general population, unless specifically tested for, leading to chronic, persistent infections. The aim of this dissertation was to …
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In silico-guided design, synthesis and antimicrobial activity of piperazine-linked 8-hydroxyquinoline-isatin hybrids
… Escherichia coli’s outer membrane protein A (OmpA) and DNA gyrase as the key target enzymes. Both 14c and 15c showed binding energies of -9.8 kcal/mol with OmpA. In the case of DNA gyrase, a binding energy of -8.9 kcal/mol was recorded for 14c, whereas 15c showed satisfactory interaction with …
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Novel Applications of Biolayer Interferometry to Investigate Molecular Interactions
… to its outer membrane host receptor protein OmpA. The use of BLI also demonstrates the technology as a probe to predict and verify binding interactions at the molecular level to assign the role of protein function in both Vibrio fischeri and Pseudomonas aeruginosa. Each aim of this research …
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The evolution of the autoantibody response in Graves’ disease
… rFab germline, KSAbl and KSAb2 showed binding to OmpA, OmpC and OmpF of Y. enterocolitica. Our findings raise the possibility that the clonal expansion of B cell populations that acquire autoreactivity in the periphery may be associated with the porin proteins of Y. enterocolitica.
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Unterschiedliche Funktionen von SRP und SecA beim Transport eines bakteriellen Proteins
… Periplasma und Aussenmembran. Proteine dieser Kompartimente müssen nach ihrer Synthese im Zytosol an ihre Bestimmungsorte transportiert werden. Für die Zielsteuerung ungefalteter Proteine an die Innenmembran und ihren anschliessenden Transport sind im wesentlichen zwei unterschiedliche …
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The influence of effective consolidation stress on the normalized extension strength properties of resedimented Boston blue clay
… stresses ranges of [sigma]'v 2 =/>10 ksc (1.OMPa). To do this, a series of Ko-consolidated undrained triaxial extension tests were performed at vertical consolidation consolidation stresses ranging from 1.5 ksc (0.15 MPa) to 20 ksc (2.0MPa). Results from these tests clearly show that the …
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Molecular Detection of Tick-Borne Pathogens Associated With Ixodid Tick Species Infesting Migratory Songbirds and Ruminants
… prevalence of SFGR were determined by amplifying ompA (outer membrane protein A) gene. The nucleotide sequence of amplicons were homologous with several SFGR including Rickettsia amblyommii, was confirmed by ompB probe based qPCR assay. Rickettsia amblyommii was found predominant in Amb/yomma …
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An Insight Into the Microbial Diversity and Expression of Cysteine Protease Inhibitors (Cystatin) in <i>Rickettsia parkeri</i> Infected <i>Amblyomma maculatum</i>
… <em>A. maculatum</em> based on rickettsial <em>ompA</em> gene PCR. Our results showed <em>A. maculatum </em>harbors <em>R. parkeri, R. amblyommii, </em>and <em>R. endosymbiont of A. maculatum.</em> While only <em>R. parkeri</em> was detected in female salivary glands which suggest its ability to …
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The Relationship Between Biofilm Production and Human Respiratory Cell Attachment and Invasion by Acinetobacter Baumannii
… with the presence or absence of target genes <em>ompA, abaI, pga operon, bap, csuE, or blaPER-1</em>. Virulence of <em>A. baumannii</em> clinical isolates increases due to their ability to produce biofilms and to attach to and invade host cells. It is important to elucidate further mechanisms of …
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Infección por Chlamydia trachomatis: una aproximación de la situación en Asturias
… Mediante PCR anidada se amplificó el gen ompA de la bacteria, para conocer su prevalencia tanto en población general asintomática, como en pacientes con prácticas sexuales de riesgo. Asimismo, se caracterizaron las diferentes variedades circulantes, con el fin de diferenciar los genotipos …
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Der Proteintransport in Rhodobacter capsulatus und Escherichia coli über das Tat-Transportsystem
… des Tat-abhängigen pSufI, des Sec-abhängigen pOmpA und des Fusionsproteins HybOmpA, das aus dem reifen Teil von OmpA und der Tat-Signalsequenz von HybA besteht, konnte gezeigt werden, dass Tat-Substrate am Ribosom wie andere sekretorische Proteine an Trigger Faktor, ein am Ribosom lokalisiertes …
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Phenotypic, Genotypic, and Pathogenic Evaluation of E. coli ST131 Clinical Isolates
… or increased numbers of virulence factors compared to other sequence types of pathogenic E. coli. To date, no data in the literature can entirely explain the global dominance of ST131 E. coli. The purpose of this study was threefold: 1) to evaluate infectivity among ST131 E. coli compared to …
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Characterization of novel virulence factors of Shigella flexneri and development of Caenorhabditis elegans as an animal model for Shigella infection
… prominent bacterial outer membrane proteins, OmpA and YaeT. This is the first report in S. flexneri where the functions of AnsB and GGT have been found to extend beyond their canonical metabolic roles. The requirement of AnsB and GGT for the virulence of S. flexneri makes these genes …
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Characterization of novel virulence factors of Shigella flexneri and development of Caenorhabditis elegans as an animal model for Shigella infection
… prominent bacterial outer membrane proteins, OmpA and YaeT. This is the first report in S. flexneri where the functions of AnsB and GGT have been found to extend beyond their canonical metabolic roles. The requirement of AnsB and GGT for the virulence of S. flexneri makes these genes …
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Investigation of Pantoea stewartii Quorum-Sensing Controlled Regulators and Genes Important for Infection of Corn
… and Lon are important to in planta growth and OmpA plays a role in plant virulence. In conclusion, these studies have broadened our understanding about the role of the QS regulon and other genes important for the pathogenesis of this phytopathogen. This knowledge may now be applied toward the …
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Zur Substratspezifität und Substratbindung des periplasmatischen Chaperons SurA aus <i>Escherichia coli</i>
… der nativen SurA-Substrate LamB, OmpF und OmpA wurden mit Wildtyp-SurA bzw. mit SurAN+ICt, einer SurA-Variante, der die aktive PPIase-Domäne PII fehlt, auf Bindung durchmustert. Mittels surface plasmon resonance (SPR) und Fluoreszenzspektroskopie wurde bestätigt, dass ein SurA-bindendes …
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Funktionelle Charakterisierung des BvgAS BH-Zwei-Komponentensystems von Bordetella holmesii
… Gattung Bordetella hoch konservierten Proteine OmpA, BvgA und BvgS die interessante Beobachtung, dass dieser Organismus in dieser Hinsicht viel mehr Ähnlichkeiten zu den „neuen“ Bordetella-Arten besitzt und in diesem Zusammenhang phylogenetisch eher im Umfeld von B. avium anzusiedeln ist. Bei …