Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"off-pathway oligomers"”.
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Self-assembly and aggregation of glucagon-like peptide 1 and its analogues
… amidated variant, GLP-1-Am. In particular, the off-pathway aggregation of GLP-1 and GLP-1-Am into disordered low-molecular weight oligomers is described. This process competes with the amyloid formation pathway and the addition of pre-formed off-pathway oligomers slightly slows down the …
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Studies on the physical stability of a C-terminally amidated variant of GLP-1
… lag times, small stable soluble peptide oligomers start to form. These oligomers, which were characterised using a number of different biophysical techniques, may be off-pathway species of amyloid fibril formation or products of partial peptide degradation. The aggregation kinetics were …