Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 27 for “"ocular surface"”.
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Role of Macrophages in Ocular Surface Fibrosis
… could cause the transdifferentiation of ocular surface fibroblasts into myofibroblasts, thus contributing to oGVHD-associated fibrosis.</p> <p>Bone marrow cells were cultured in M-CSF to obtain M0 macrophages, which were subsequently polarized into M1 and M2 phenotypes using IFN-g + LPS …
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The Role of Hyaluronan in the Ocular Surface
… all tissues of the body, including maintaining ocular surface homeostasis. Hyaluronan (HA) is found in the extracellular matrices of the corneal limbus and meibomian gland (MG). This dissertation evaluated the role of hyaluronan in ocular tissues, particularly in the limbal stem cell niche and …
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Clinical Applications of Stem Cells in Ocular Surface Reconstruction.
… cells on amniotic membrane for the treatment of ocular disorders. This thesis is primarily a microscope-based study and documents the findings of several investigations designed to refine tissue engineering of the cornea. Light, scanning and transmission electron microscopy were used to study …
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AMNIOTIC MEMBRANE TRANSPLANTATION FOR OCULAR SURFACE RECONSTRUCTION IN VETERINARY MEDICINE
… reconstruction of corneal and/or conjunctival surface in different diseases, such as: ocular surface neoplasia, pterygium, chemical and thermal burns, cicatrizing conjunctivitis, symblepharon release, bleb leakage, filtering surgery, persistent epithelial defects, non healing stromal ulcers, …
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Effect of Diabetes Mellitus on Ocular Surface Tight Junctions and Glycocalyx
… cataract, glaucoma, papillopathy, and ocular surface disease. Ocular surface abnormalities in patients of diabetes mullites include impairment of corneal epithelial barrier function, conjunctival defects, increased incidence of corneal and conjunctival infections and higher prevalence …
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Evaluating the Role of the Ocular Surface Microbiome in Dry Eye Disease Mediated Neural Dysregulation
Dry eye disease (DED) is a multifactorial ocular surface disorder arising from a loss of homeostasis at the corneal-tear interface. This leads to visual and neurosensory abnormalities which are regulated by the corneal-trigeminal ganglion pathway. An important contributor to ocular homeostasis is …
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Cell and Tissue Therapy of the Anterior Ocular Surface // Клетъчна и тъканна терапия на предна очна повърхност
Трансплантацията в офталмологията е област с нови и бързо развиващи се перспективи, което ще позволи приложение на хибридни технологии и тъканно инженерство с цел постигане на по-добри оптични резултати и хомеостаза на предната очна повърхност. Целта на разработката е да се направи анализ на …
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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus
… the severity of diabetes-mediated injury to the ocular surface and its various components like tear film, goblet cells and glycocalyx, has not yet been investigated. These pathological changes can potentially cause dry eye and corneal injury including epithelial erosion, impaired wound healing …
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Aligning Eye Care Provider Beliefs with Behaviors: Exploring and Improving Ocular Surface Disease Decision-making in a Cataract Surgery Clinic
… in the medical literature to identify and manage ocular surface disease prior to surgery. As a result, patients risk suffering several significant consequences with regard to their vision, comfort and safety. Personal observations from my 25 years of experience working with ophthalmologists and …
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TOLL-LIKE RECEPTOR EXPRESSION AND FUNCTION
Purpose: Ocular surface inflammation presents from various etiologies (e.g. dry eye and Pseudomonas aeruginosa (PA) infection), yet little is known about the role of toll-like receptors (TLR) which, upon activation, stimulate inflammation. The objective of this research was to determine: (1) …
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… immune cells to host organs, including the eye surface. Mostly based on the time of disease onset after transplantation, GVHD is divided into the acute and chronic phase. The eyes may be involved in both acute and chronic GVHD, although ocular involvement is more common in the chronic GVHD with …
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Avaliação da superfície ocular em pacientes com doença ocular da tireoide
… disease, affecting 25-50% of these patients. Ocular surface disease (OSD) is a multifactorial disorder characterised by an imbalance in tear film homeostasis, resulting from deficient tear production and/or excessive tear evaporation. In TED, the enlargement of the palpebral fissure, combined …
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Corneal Surface Changes and Subjective Symptoms After Cataract Surgery
… B. 각막표면 형광염색검사 8 C. 쉬르머검사 (Schirmer test) 10 D. Ocular surface disease index (OSDI) 11 Ⅳ. 고찰 14 Ⅴ. 결론 20 참고문헌 21 APPENDIX 25 ABSTRACT 27 "
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Microstructural Analysis and Assessment of the Anterior Ocular Surface Damage Caused by Ultraviolet Light from Natural and Artificial Sources // Възможности за микроструктурен анализ и оценка на уврежданията на предната очна повърхност от ултравиолетови лъчи с естествен и изкуствен произход
Трудът оценява и описва микроструктурните промени на очната повърхност, получени в отговор на излагане на УВ светлина от естествен и изкуствен източник. Резултатите са съпоставени със слънцезащитните навици като се проследява тяхната динамика, използвайки in vivo конфокална микроскопия. За период …
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Intense Pulsed Light for the Treatment of Evaporative Dry Eye
… in the signs and symptoms of EDE after periocular application, but possible mechanism(s) of action of IPL in the context of long-term MGD management remain poorly understood. Purpose To explore the dry eye practices of New Zealand eyecare professionals against current evidencebased …
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An Investigation of the Role of Bacillus oleronius in the Pathogenesis of Rosacea
… rosacea have symptoms that manifest in the periocular region, including irritation, inflammation of the eyelids (blepharitis), increased vascularisation of the ocular surface and in severe cases inflammation of the cornea (keratitis) can develop leading to sterile ulcers and visual impairment. …
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Contact Lenses as Optical and Protective Element of the Front Ocular Surface. Issues and Future of Contactology in Bulgaria, the Balkans and Europe // Контактните лещи — оптичен и протективен елемент на предната очна повърхност. Контактологията в България, на Балканите и в Европа — проблеми и перспективи
Главна цел на настоящото проучване е да се тестват и установят стандарти за добра контактологична практика в България, съобразени с Европейската и световната контактология чрез: определяне на познанията за контактните лещи сред популацията в България и на Балканите, дефиниране на характеристиките …
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Structural and functional characteristics of meibomian glands in meibomian gland dysfunction
… morphology; to evaluate meibum composition and ocular surface signs and symptoms associated with morphological changes in the glands before and after treatment for Meibomian gland dysfunction (MGD). Methods: There were five method development studies and one clinical trial. The first two studies …
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The Impact of a Scleral Lens on the Eye
Purpose: There are several gaps in understanding ocular effects of a scleral lens (SL), particularly in the composition of the fluid reservoir (FR) that bathes the cornea and the impact of the landing zone radius (LZR) on the eye. The purpose of this dissertation is to (1) identify and compare …
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Characterisation of 11beta hydroxysteroid dehydrogenase 1 in ocular and orbital tissues
… inflammation. The first line of defence in the ocular tissues includes the mucosal barrier and expression of receptors that recognise pathogen. These mechanisms activate the innate immune response during inflammation, however, in the ‘normal’ eye, immunomodulatory components exist to promote …
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