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Showing 1 to 3 of 3 for “"octamer element"”.
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The Dual Role of OCA-B in B Cell Development and Signaling
… OCT-2. OCT-1 or OCT-2 can bind an upstream octamer element with the consensus sequence 5'-ATGCAAAT-3' in target gene promoters and enhancers. At the octamer element, the OCT-1/2-OCA-B complex is able to regulate gene expression via interaction with the basal transcription machinery. OCA-B …
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Purification and Characterization of OTF-1, A Transcription Factor Regulating Cell Cycle Expression of a Human Histone H2b Gene: Demonstration of its Functional Identity with NF-III, a Factor Required for Efficient Initiation of Adenovirus DNA Replication
<p>An octamer-binding transcription factor, OTF-1, which stimulates transcription of a human histone H2b gene, has been purified from HeLa nuclear extracts. This purification was achieved through the use of DNA affinity chromatography, and the factor was unambiguously identified by renaturation of …
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Old protein, new perspective : the role of Oct-1 during embryonic development and lymphopoiesis
… process involves the interaction of cis acting elements with trans acting factors. The octamer element (5'ATGCAAAT-3') is conserved in Ig promoters and enhancers and is thought to be important in transcriptional regulation. To date, only two octamer-binding proteins have been identified in B …