Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"ochratoxin A"”.
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Screening der apoptoseinduzierenden Interaktionen von Nephrotoxinen unter besonderer Berücksichtigung von Ochratoxin A
Ochratoxin A ist ein Schimmelpilzmetabolit, der in vielen Nahrungsmitteln des Menschen vorkommt und in <80% der Blutproben nachweisbar ist. OTA wirkt hauptsächlich auf die Niere, und hier unter anderem durch Apoptose. Im täglichen Leben sind wir jedoch vielen Nephrotoxinen gleichzeitig ausgesetzt. …
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Modulating effects of Fumonisin B1 and Ochratoxin A on immune cells in human carcinoma
Thesis (Doctor of Technology: Clinical Technology), Durban Institute of Technology, Durban, South Africa, 2005
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Wirkung nanomolarer Konzentrationen des Mykotoxins Ochratoxin A auf Calciumhomöostase, Wachstumsverhalten und hormonelle Signaltransduktion menschlicher proximaler Tubuluszellen
… weitverbreitete und karzinogene Pilzmetabolit Ochratoxin A (OTA) beeinflußt die Funktion und das Wachstumsverhalten renaler Zellen. In höheren Konzentrationen reduziert OTA auch die Integrität der Zellen. Untersucht wurde die mögliche Beteiligung von Änderungen der zellulären Calciumhomöostase …
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Study of Ochratoxin A biosynthesis by Aspergillus ochraceus and incidence of ochratoxigenic fungi on Wine Grapes from Southern Illinois
Ochratoxin A (OTA) is a neurotoxic, immunotoxic, and teratogenic mycotoxin produced by many <Aspergilli> and <Penicillia>. These organisms infect several plant species at pre-harvest and post-harvest and produce OTA in the infected crops. To date, little is known about the mechanisms that regulate …
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Development of a novel monoclonal antibody-based immunoaffinity column for the detction of aflatoxins
… intraperitoneally with aflatoxin B1 and ochratoxin A protein conjugates. The main characteristic of these monoclonal antibodies is their ability to bind sufficiently better to all four main aflatoxins and ochratoxin A than other antibodies already on the market. Past studies have shown …
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Entwicklung flüssigkeitschromatographisch-massenspektrometrischer Methoden zum Nachweis von Mykotoxinen im Hausstaub
… Die Mykotoxine Citrinin, Deoxynivalenol, Ochratoxin A und Sterigmatocystin wurden im unteren µg/kg Hausstaub Bereich quantifiziert. Ein eindeutiger Zusammenhang zwischen einem Schimmelpilzbefall und den nachgewiesenen Mykotoxinen konnte nicht festgestellt werden. Mittels verschiedener …
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Food safety in wine: optimization of analytical controls and evaluation of production technologies
… on human health, such as biogenic amines and ochratoxin A in wines. Therefore, the influence of production technology (pH, amino acids precursor and use of different malolactic starters) on biogenic amines content in wines was evaluated. An HPLC method for simultaneous determination of amino …
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Nachweismethoden für Schimmelpilze und deren Metaboliten in Innenräumen
… Die Mykotoxine Sterigmatocystin und Ochratoxin A waren in einigen Hausstaubproben nachweisbar, ohne dass ein direkter Zusammenhang zu einem Pilzbefall im Haushalt hergestellt werden konnte.
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Identification and Characterization of Novel Mycotoxin Degrading Enzymes
… a novel thermophilic bacterium that degrades Ochratoxin A was discovered. Additionally, a zearalenone hydrolase previously identified with the pipeline was biochemically characterized and demonstrated to hydrolyze additional resorcylic acid lactones beyond zearalenone, including radicicol. …
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Characterization of Understudied Risk Factors in Chronic Kidney Disease
… the contribution of one proposed CKDu driver, ochratoxin A (OTA). It will also explore the kidney injury mechanisms of post-translationally modified albumin using human-relevant in-vitro systems. This latter set of experiments sheds light on CKD more generally.Chapter 2 defines OTA’s …
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An assessment of gastric cancer associated factors and strategies for early case detection in patients seen at the university teaching hospital in Lusaka, Zambia.
… (IQR 1.7- 40) ng/mg creatinine, while 96% had ochratoxin A in their blood median; 0.1 ng/ml (IQR 0.2-0.6 ng/ml). Being Helicobacter pylori (H. pylori) seropositive (determined by the presence of at least four antibodies) was not associated with either GA (OR 1.1; 95% CI 0.5-3.3) or GP (OR 1.9; …
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An assessment of gastric cancer associated factors and strategies for early case detection in patients seen at the university teaching hospital in Lusaka, Zambia.
… (IQR 1.7- 40) ng/mg creatinine, while 96% had ochratoxin A in their blood median; 0.1 ng/ml (IQR 0.2-0.6 ng/ml). Being Helicobacter pylori (H. pylori) seropositive (determined by the presence of at least four antibodies) was not associated with either GA (OR 1.1; 95% CI 0.5-3.3) or GP (OR 1.9; …
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Nutritional strategies to control mycotoxin damages in swine
… that cause health and economic problems. Ochratoxin A and fumonisin B1 have been classified by the International Agency for Research on Cancer in 1993, as “possibly carcinogenic to humans” (class 2B). To control mycotoxins induced damages, different strategies have been developed to reduce …
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Toxicity of mycotoxins to insects and underlying molecular and biochemical mechanisms
… display substantially higher tolerance of ochratoxin A (OTA) than do H. zea. Honey bees and their resource-rich nests are hosts to a wide range of saprophytic fungi, including species that produce mycotoxins. Bioassays showed that the honey bee workers can tolerate relatively high levels of …