Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"object recognition memory"”.
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The Short and Long-Term Effects of Chronic Ketamine during Adolescence on Object Recognition Memory in Rats
… demonstrated that ketamine causes deficits in object recognition and location memory following both acute and chronic administration (Pitsikas & Boultadakis, 2009; Venãncio et al., 2011). Although it is well established that abuse of many different kinds of drugs during the critical …
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The Effect of Selective Cholinergic Lesion of Medial Septum on Recognition Memory
The objective of this study was to clarify the role of septal-hippocampal cholinergic neurons in object and spatial recognition memory. Stereotaxic-surgical infusion of the selective cholinergic neurotoxin, 192IgG-saporin (SAP), into the medial septum (MS) of Sprague-Dawley rats was utilized to …
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Functional dissociation between the hippocampal formation and perirhinal cortex : evidence for independent memory systems in the medial temporal lobe
… views about the functional organization of memory in the medial temporal lobe of the mammalian brain suggest that the hippocampal formation (HPC) and the perirhinal cortex (PRh) are serial components in a unitary memory system. Contradictory to this view, evidence from numerous studies with …
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Adult behaviour and cerebral cell densities after maternal or post-weaning consumption of an obesogenic diet in mice
… interaction (for social preference) and novel object recognition (for object recognition memory) tasks. At 14 weeks of age, the offspring were killed and their brain collected for regional analysis of neuron and glia densities. Behavioural and cell density data were analysis by two-way ANOVA …
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Disambiguating the Similar: Investigating Pattern Separation in Medial Temporal Lobe Structures Using Rodent Models
… but often overlooked fact that successful memory involves more than just remembering events over a period of time, but also differentiating between similar memories. Through a series of experiments this dissertation adds support to the literature that the dentate gyrus (DG) subregion of the …
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A non-human primate model of dorsolateral prefrontal cortex dysfunction in schizophrenia
Spatial working memory (SWM) impairment is a key cognitive symptom of schizophrenia, for which no effective treatment currently exists. In order to develop new treatments, we must better understand how these deficits arise from structural and functional changes within the neural circuits supporting …
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Cognitive Mechanisms of Memory Impairment Following Traumatic Brain Injury
Memory impairment is common following traumatic brain injury (TBI). In recent years, researchers have demonstrated that the processes underlying memory formation (working memory, encoding, consolidation, and retrieval) are interrelated but dissociable events.The following study was designed to …
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Ruolo del recettore CB1 cellulare e sub-cellulare in cellule D1-positive dell'Ippocampo nei Processi della Memoria
… a major brain modulatory system controlling memory functions. On the other hand, several reports point out a crucial role of hippocampal dopamine signaling in the regulation of memory related processes. Furthermore, recent evidence suggests that hippocampal cells expressing dopamine receptors …
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The effects of licorice root components on cognition
… shown that estrogens can modulate learning and memory. Importantly, the effects of estrogens on cognition vary based on several factors including dose, the type of estrogen used, the age of the animal, the length of exposure, the route of exposure, as well as the demands of the cognitive task. …
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Effects of alcohol and ∆9-tetrahydrocannabinol on energy balance and cognitive behaviors
… (for 14 weeks) did not appreciably alter object recognition memory and emotion-like behavior in both sexes of rats. But such drinking pattern and duration altered glucose homeostasis in males. Chapter 4 established two rodent models of alcohol and THC co-use that differed in terms of the …
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Hypoxic immunomodulation results in increased disease risk and altered behavior via non-canonical pathways
… of acute hypoxia on hippocampal-independent memory recall and particular cellular localization of inflammasome activity within the amygdala. Mice were exposed to hypoxic (6% oxygen/94% nitrogen) or normoxic (ambient) conditions for a period of 2 hours. Following 2 hours of reoxygenation, mice …
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Mathematical models of cognitive processes
… activity during cognitive processes, such as object recognition, memory, language, attention; 2) the second one concerns the mathematical modelling of multisensory integration processes (e.g. visual-acoustic), which occur in several cortical and subcortical regions (in particular in a …