Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"nucleotidyltransferase"”.
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Identification of proteins interacting with lupin and Arabidopsis tRNA nucleotidyltransferases
ATP (CTP):tRNA nucleotidyltransferase catalyzes the addition of CMP and AMP residues to the 3 ' ends of tRNAs that have an incomplete CCA sequence. In eukaryotic cells, nuclear, mitochondrial and chloroplast genomes all encode tRNAs. Therefore, although tRNA nucleotidyltransferase is synthesized in …
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Synthesis and Evaluation of Densely-Functionalized Troponoids
… resistance enzyme known as aminoglycoside-2’’-O-nucleotidyltransferase [ANT(2’’)-Ia]. Enzymatic mechanistic insights have been gleaned from an assessment of troponoid/antibiotic synergistic potential. In particular, two synthetic constructs were identified as promising antibiotic adjuvant …
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Molecular mechanisms of the carcinogen chromium(VI)-induced DNA-protein crosslinking in cultured intact human cells
… in GeneBanks. Actin, lectin, and aminoglycoside nucleotidyltransferase were identified as participants in chromate-induced DNA-protein crosslinking. (5) DNA protein complexes as a biomarker of exposure to chromate: Finally, DNA-protein crosslinks were detected immunologically by developing an …
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Investigating the biosynthesis of fosfazinomycin
… the discovery of a PqqD-like enzyme and a nucleotidyltransferase homolog that may be involved in fosfazinomycin biosynthesis. How the N-N bond is crafted in fosfazinomycin still remains a mystery. Chapter 5 recounts my failed efforts towards reconstituting the enzymatic formation of the N-N …
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Structural and Functional Studies of the SARS-CoV-2 NiRAN Domain
… of the SARS-CoV-2 Nidovirus RdRp-associated nucleotidyltransferase (NiRAN) domain is essential for viral propagation, with three distinct activities associated with modification of the nsp9 N terminus, NMPylation, RNAylation, and deRNAylation/capping via a GDP-polyribonucleotidyltransferase …
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Biochemical and structural studies of RNA damage and repair in bacteria
… Ligase-associated Polβ). RlaP-NTase is a novel nucleotidyltransferase (NTase) of the Polβ superfamily. NTases are known to transfer NMP from an (d)NTP onto an acceptor molecule, such as an RNA, DNA, protein, or small molecule. The Polβ superfamily is very large and highly diverse family which …