Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1899 for “"nucleotide"”.
-
Nucleotide Inhibition of Glyoxalase II
… Studies indicate that inhibition of Glo-II-s by nucleotides is restricted to ATP, GTP, ADP, and GDP, with ATP appearing most effective. Kinetics studies have shown that ATP acts as a partial non-competitive inhibitor of Glo-II-s activity, and further suggest that two kinetically distinguishable …
-
Diphosphopyridine Nucleotide Binding by Apodehydrogenases
Made available in DSpace on 2014-12-05T19:37:17Z (GMT). No. of bitstreams: 1 6000199.pdf: 3037417 bytes, checksum: 6d6ee9972aa702d714e7ffab685be9a1 (MD5) Previous issue date: 1959
-
Factors Influencing Muscle Purine Nucleotide Metabolism.
… the factors influencing the metabolism of purine nucleotides in human skeletal muscle, plasma and urine. Study one investigated the influence of the number of intermittent sprint bouts and the subsequent accumulation of plasma purines and urinary purine excretion. Study two investigated the …
-
Assessing Microbial Diversity Through Nucleotide Variation
… at finer scales of microbial communities through nucleotide variation in 16S rRNA genes.
-
Algorithms for estimating rates of nucleotide change
… acquisition of genome-wide data for estimating nucleotide rates not only including mutation rates within species, but including substitution rates between species from multiple sequence alignments. To address the problem of estimating mutation rates within species, Vogl (2014) has developed a …
-
Algorithms for estimating rates of nucleotide change
… acquisition of genome-wide data for estimating nucleotide rates not only including mutation rates within species, but including substitution rates between species from multiple sequence alignments. To address the problem of estimating mutation rates within species, Vogl (2014) has developed a …
-
Novel acyclic nucleotide phosphonates against RNA viruses
Acyclic nucleotide phosphonates (ANPs) have been used for years as successful anti-viral agents against diseases such as HIV/AIDS and hepatitis while the drug ribavirin is one of the only drugs available for the treatment of RNA-viral infections which mainly affect the developing world. The large …
-
Analyse von Single Nucleotide Polymorphisms an Glas-Oberflächen
Ziel der vorliegenden Arbeit war die Entwicklung einer SNP-Genotypisierungsmethode mit auf Mikroarrays immobilisierten PCR-Produkten. Für die Analyse wurde ein faseroptischer Affinitätssensor bzw. ein Durchfluss-Biochip-Scanner mit integrierter Fluoreszenzdetektion verwendet. An den immobilisierten …
-
Biochemical pharmacology of nucleotide metabolism in rat hepatoma
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
Linear clustering with application to single nucleotide polymorphism genotyping
Single nucleotide polymorphisms (SNPs) have been increasingly popular for a wide range of genetic studies. A high-throughput genotyping technologies usually involves a statistical genotype calling algorithm. Most calling algorithms in the literature, using methods such as k-means and mixturemodels, …
-
Novel nucleotide analogues for forming stable DNA triple helices
… are formed by binding of a triplex-forming oligonucleotide (TFO) to a DNA duplex, via specific recognition of the individual base pairs in the target sequence.<br/>Mixed-sequence recognition of duplex DNA by TFOs is therefore an essential requirement for successful targeting. However, achieving …
-
ADP-Heptose and Nucleotide Enhancers Drive Fusobacteria-Induced Inflammation
… molecular pattern ADP-heptose and ribonucleotides that together, but not individually, strongly induced NF-<em>κ</em>B signaling as well as the expression of inflammation and cancer associated genes. This finding suggests a regulatory role for extracellular nucleotides in ADP-heptose …
-
Multiplexed genotyping of single nucleotide polymorphisms using microarray technology
… the unique feature of TdT to polymerize oligonucleotides in a template-independent manner, another novel and versatile tool (TAPE) was established and it demonstrated great potential in genomic analyses, mainly genotyping and gene expression. Finally, an unusual property of TdT was discovered …
-
Pyrimidine nucleotide carrier 1 in mitochondrial homeostasis and cancer
… work has examined the significance of pyrimidine nucleotide carrier 1 (PNC1), an Insulin like Growth Factor 1 (IGF- 1)-inducible mitochondrial Uridine-5'-triphosphate (UTP) transporter in cancer. Loss of PNC1 is lethal, while suppression of PNC1 in cancer cells has been demonstrated to induce …
-
The nucleotide binding domains of multidrug resistance-p-glycoproteins
Bibliography: leaves 116-128.
-
ClpX interactions with ClpP, SspB, protein substrate and nucleotide
ClpXP and related ATP-dependent proteases are implements of cytosolic protein destruction. They couple chemical energy, derived from ATP hydrolysis, to the selection, unfolding, and degradation of protein substrates with the appropriate degradation signals. The ClpX component of ClpXP is a …
-
Studies on pyridine nucleotide-dependent processes in Haemophilus influenzae
… NAD; therefore, several pyridine nucleotide-requiring enzymes become important for the survival of these pathogens. Haemophilus influenzae ATP:NMN adenylyltransferase was partially purified 15-fold with a 27% yield using dye affinity chromatography. Affinity chromatography was also …
-
Single Nucleotide Polymorphisms Linked to Essential Hypertension in Kasigau, Kenya
… important. In this study, three single nucleotide polymorphisms (SNPs) known to be linked to an increase in susceptibility to EH were quantified from a cohort of Kenyans living in the Kasigau region. The SNPs are located in three genes that are part of the renin angiotensin system, the …
Page 1 of 95