Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"nucleosome dynamics"”.
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Regulation of nucleosome dynamics
… genome is packed into fundamental units called nucleosomes, where 147 base pairs of DNA are wrapped around a protein core. Stable packing of DNA in nucleosomes imposes a barrier for accessibility of genetic code on DNA for replication, transcription, and repair. The dynamics of nucleosomal DNA …
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The Influence of DNA Methylation on Both H2A.Z Nucleosome Dynamics and the Zinc Finger and Homeoboxes Transcription Factor Family
… We find that DNA methylation impacts H2A.Z nucleosome dynamics via both physical destabilization effects and influences on H2A.Z-specific nucleosome remodeler activity. Using single particle cryo-EM, we solved structures of human H2A.Z nucleosomes on methylated and unmethylated DNA, …
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Transcription and chromatin dynamics in the Notch signalling response
… of the chromatin environment. To learn about the dynamics of the Notch transcriptional response, a live imaging approach was used in Drosophila Kc167 cells to visualise the transcription of a Notch-responsive gene in real time. With this technique, it was found that Notch receptor cleavage and …
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DYNAMICS OF NUCLEOSOME REMODELING BY ATP-DEPENDENT CHROMATIN REMODELERS
… on DNA, break histone-DNA contacts, and mobilize nucleosomes. However, the final outcomes of nucleosome remodeling are diverse - nucleosome sliding, dimer exchange, nucleosome disassembly, and nucleosome conformation alteration. This study sheds light on how different chromatin remodelers catalyze …