Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"nucleoid associated proteins"”.
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Nucleoid-Associated Proteins of Streptomyces coelicolor: Discovery and Functions
… problematic. The role of the architectural nucleoid-associated proteins (NAPs) in regulation of the expression of these products has been neglected within the Actinomycetes. NAPs are small, highly abundant proteins which govern both gene expression and nucleoid structure on a genome-wide …
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Interactions between nucleoid associated proteins and DNA in the presence of mechanical and chemical forces
… smaller cell, but must also be accessible to proteins responsible for biological processes. Architectural proteins assist with this large-scale arrangement of DNA to achieve the correct balance between these two competing requirements. The structural proteins that interact with DNA in …
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Transposable prophage Mu exists as an independent chromosomal domain in E. coli
… mechanisms like transcription and DNA-binding proteins. We find that transposable prophage Mu, transcriptionally silent by definition, is organized into an independent domain as determined by the close proximity of Mu termini L and R separated by a 37 kb Mu genome. Cre-loxP recombination is …
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New mechanisms in transcription regulation and chromosome organization in Caulobacter crescentus
… of transcription is often carried out by proteins, called transcription factors, that interact with DNA or RNA polymerase (RNAP) or both, and can change the preference of RNAP for target promoters. Additionally, DNA is tightly compacted and organized inside cells. In bacteria, …
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Investigating the Biological Role and Binding Modes of Histone-Like Proteins of Halophilic Archaea
… However, the role of the histone-like proteins of halophilic archaea is unclear. Previous work in the model species Halobacterium salinarum indicated that its sole histone gene, hpyA, is dispensable for growth and is expressed at very low levels. I hypothesize that the unique high-salt …
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The iron-dependent cyanide and hydrogen peroxide co-toxicity in Escherichia coli and its catastrophic consequences for the chromosome
… demonstrated that this synergistic toxicity is associated with catastrophic chromosomal fragmentation, which is blocked by iron chelators. Moreover, the CN + H2O2 treatment also resulted in destruction of ribosomal RNA, indicating that RNA is equally susceptible to the oxidative damage induced. …
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Molecular mechanisms underlying regulation of type III secretion system upstream of the master regulator HrpL in Erwinia amylovora
… hrpL and other T3SS gene expression. IHFs are nucleoid-associated proteins and consist of two subunits, i. e. IHFα and IHFβ. IHFα and IHFβ usually form heterodimers, which could influence nucleoid structure and gene expression via DNA bending. Two single mutants (ihfA and ihfB) were generated …