Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"nucleic acid amplification tests"”.
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Novel and newer nucleic acid amplification tests for the diagnosis of TB
… of the promising novel loop mediated isothermal amplification (LAMP) assay on sputum, and that of the semi-automated Xpert MTB/RIF (Xpert) test on non-sputum specimens (bronchoalveolar lavage fluid [BALF], tracheal aspirates, and cerebrospinal fluid [CSF]) from South African patients with …
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Diagnostic Accuracy of Nucleic Acid Amplification Tests in Urine for Pulmonary Tuberculosis: A Meta-Analysis
… the diagnostic accuracy of tuberculosis nucleic acid amplification tests (NAATs) in urine samples for active pulmonary tuberculosis (PTB). <bold>Design:</bold> Systematic review and meta-analysis. Electronic databases and reference lists were searched without language, setting or time …
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The Exploration and Development of Focused Ultrasound Extraction (FUSE) for the Rapid Release of DNA from Complex Tissue Matrices
… of simpler, faster, and more accessible nucleic acid amplification tests (NAATs) that have enabled point-of-contact (POC) DNA testing, delivering real-time results in resource-limited settings. Despite these advancements, the DNA sample preparation process is laborious, …
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A clinical and molecular analysis of Clostridium difficile strains isolated from Groote Schuur Hospital
… method, enzyme immunoassay-based detection tests (Meridian ImmunoCard and bioMérieux MiniVidas) were found to be lacking clinical sensitivity, while nucleic acid amplification tests (Hain Lifescience CDiff and Cepheid GeneXpert) were far more sensitive in the local clinical setting. PCR …
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Isothermal Nucleic Acid Assays for the Detection of HIV Drug Resistance and Sickle Cell Disease in Low-Resource Settings
… goal of this thesis work was to develop low-cost nucleic acid tests that can improve early detection of these two conditions in low-resource settings. The first part of this thesis work focused on the development of a method to discriminate M184V, the most common HIV-1 drug resistance mutation, …