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Showing 1 to 4 of 4 for “"nuclear speckle"”.

  1. Nuclear speckle dynamics and function of speckle association in gene expression

    Nuclear speckles have been studied intensively for a long time. Accumulating evidence has suggested that nuclear speckles have a dynamic structure, and are associated with a significant fraction of active chromosome regions and genes. However, their mobility and the regulation mechanism of their …

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  2. Computational approaches for analyzing regulatory regions in the human genome

    … cytological distance of chromatin to a specific nuclear structure. Norma is an all-in-one software package for TSA-seq data processing, which covers from the mapping of the raw NGS reads, to the calculations of the enrichment score and conducting all kinds of the integrated analysis of enrichment …

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  3. Mechanisms and functional significance of nuclear compartmentalization

    … For better understanding of the effects of nuclear repositioning of a gene locus on gene expression, I investigated the physiological significance and mechanism of association of a gene locus with a nuclear sub-compartment. In chapter 1, I showed an actin dependent association of HSP70 …

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  4. Changes in large-scale chromatin structure and dynamics of BAC transgenes during transcriptional activation

    Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by William Ingram (wingram2@illinois.edu) on 2010-05-14T20:52:51Z Item is restricted until 2012-05-14T20:52:43Z

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