Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"nuclear mRNA"”.
-
Investigating Mechanisms of Nuclear mRNA Export
… in the cytoplasm has important implications for nuclear export and retention of mRNAs. This division ensures that only correctly processed mRNAs are exported to the cytoplasm to be translated into proteins, while misprocessed and aberrant transcripts are retained in the nucleus to be degraded by …
-
The role of human and Drosophila NXF proteins in nuclear mRNA export
… cells is the spatial separation of the site of mRNA synthesis (nucleus) from the site of mRNA function (cytoplasm) by the nuclear envelope. As a consequence, mRNAs need to be actively exported from the nucleus to the cytoplasm. At the time when this study was initiated, both human TAP and yeast …
-
Purification, characterization and substrate specificity of a nuclear mRNA (Guanine-7)-Methyltransferase from Ehrlich ascites cells
The 5' - termini of most eukaryotic and viral mRNAs contain the sequence of m7G(5')ppp(5')N- known as the "cap" structure. The guanine-7 methylation of this cap structure is important for mRNA processing and initiation of translation. A RNA (guanine-7)-methyltransferase that specifically methylates …
-
A flow cytometry-based method for gene expression profiling of CNS cell types
… from CNS subtypes and microarray analysis of nuclear mRNA. When compared to an existing technique, translating ribosome affinity purification, it was found that FANS was able to detect differentially expressed genes between two types of medium spiny neurons in the striatum with similar or …
-
The Roles of Rnt1 and Putative Endoribonucleases in Eukaryotic mRNA Degradation
… studied, especially with regard to their role in nuclear mRNA degradation. Rnt1 is a <em>Saccharomyces cerevisiae</em> (budding yeast) nuclear endoribonuclease and homolog of human Drosha with well-characterized roles in the processing of ncRNAs. The enzyme recognizes and cleaves double-stranded …