Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"nuclear import/export"”.
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Comprehensive single and paired drug target identification in healthy and disease models of NF-kB pathway
Nuclear NF-[kappa]B ("NF-[kappa]Bn") is a transcription factor responsible for regulating many genes that play important roles in inter- and intra-cellular signaling, cellular stress responses, cell growth, survival and apoptosis. Defective levels of NF-[kappa]Bn has been associated with cancer, …
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The Influenza A Virus NS1 Protein and Vriral mRNA Nuclear Export
… both the viral genome (vRNA) and mRNA must be exported from the nucleus to the cytoplasm. The mechanism by which vRNA nuclear export is achieved has been well characterised, but how viral mRNAs are exported is poorly understood. The cellular NXF1-dependent mRNA export pathway has been shown to …