Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"nuclear factor-κ"”.
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Targeting Traf6 For Cancer Therapeutical Development
<p>Tumor necrosis factor (TNF)-Receptor Associated Factors (TRAFs) are a family of signal transducer proteins. TRAF6 is a unique member of this family in that it is involved in not only the TNF superfamily, but the toll-like receptor (TLR)/IL-1R (TIR) superfamily. The formation of the complex …
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Autoimmune Responses to Atherosclerotic Lipids: A Study In Murine Models of Atherosclerosis and Obesity
… db/db mice with hyperlipidemia. Tumor necrosis factor-alpha (TNF-α) was increased in db/db spleen, while TNF-α receptor expression augmented in the db/db murine heart, in comparison with those in normal mice. The nuclear factor-κ B (NF-κB) expression was enhanced in the db/db heart, whereas …
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Cerebrovascular and Neuronal Cellular Consequences of Amyloid-β Induced Nuclear Factor-κB Activation
… significant role in inflammatory responses, the nuclear factor-κB (NF-κB) pathway is hypothesized to play such a regulatory function in AD.</p> <p>The work presented here examines the cellular activation of NF-κB by Aβ aggregates in both cerebrovascular and neuronal cells. Small Aβ aggregates …