Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"npr-1"”.
-
The Neural Circuitry Of Social Behavior In C. elegans
… allele of the neuropeptide y receptor homologue npr-1 promotes social feeding, while a high activity form—which is found in the wild-type N2 strain—promotes solitary behavior1. Expression of a high-activity npr-1 cDNA specifically in the interneuron RMG converted npr-1 loss-of-function mutants …
-
The Neural Circuit for Behavioral Responses to Pheromone and Social Behavior in Caenorhabditis Elegans
… with null mutation in the neuropeptide receptor npr-1 have reduced avoidance of ascr#3/C9. I found that this effect is mediated by ADL participation in a gap junction circuit with the "social" hub interneuron RMG. Thus ADL chemical synapses and ADL gap junctions appear to have antagonistic …
-
Identification and Characterization of Ethanol Responsive Genes in Acute Ethanol Behaviors in Caenorhabditis elegans
… using the basal gene expression differences in npr-1(ky13) mutant animals to enrich for genes involved in AFT. This analysis revealed ethanol changes to the expression of genes involved in a variety of biological processes including lipid metabolism. We focused on a gene involved in the …
-
Characterisation of new regulators and neural plasticity of the O2-sensing circuit in Caenorhabditis elegans
… mutation in the neuropeptide receptor 1 (npr-1). This mutation, among other things, sculpts the flow of information in the O2-circuit and prevents O2-evoked Ca2+ responses in the sensory neuron ADL. Here, we perform a forward genetic screen to isolate mutants that confer O2-escape …
-
Genetic Variation in Neurotransmitter Receptors Generates Behavioral Diversity
… in the neuropeptide Y receptor homologue npr-1 contributes to social behavior variation, but I found that other genes are also involved in this behavior. Through quantitative genetic analysis I identified polymorphisms in the GABA-gated cation channel exp-1 that generate variation in …
-
An analysis of ethanol-induced behavioural plasticity in Caenorhabditis elegans
… ethanol. However the neuropeptide<br/>receptor NPR-1, previously shown to impact on ethanol responses in C. elegans, had<br/>no effect on withdrawal behaviour in these assays. Alterations in intoxication and<br/>withdrawal behaviour in strains of worms depleted in 5-HT (tph-1) and …