Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 24 for “"novel interventions"”.
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Novel Interventions to Improve Cerebral and Peripheral Vascular Function
… vascular dementia and stroke. Identifying interventions that can attenuate the age-related decline in CBF and enhance cerebrovascular function are essential, especially in individuals at high risk of CVD. Remote ischaemic preconditioning (rIPC), which involves cyclical periods of …
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Novel interventions for increasing fruit and vegetable consumption in the workplace.
… the use of the workplace to test healthy eating interventions. Past research also suggests increased self-efficacy and a game-based approach may be advantageous to increase FV intake. The present study comprised 3 studies. Study 1 tested a poster intervention in 9 workplace canteens; study 2 …
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The Utilization and Validation of the Human Factors Intervention Matrix and the Companion Assessment Tool FACES in the Development of Novel Interventions
… tool FACES regarding developing and ranking novel interventions. This was completed by 1. Uncovering whether brainstorming with HFIX generated a higher quantity, quality, and broader breadth of ideas compared to traditional brainstorming, and 2. Seeing whether the modality in which HFIX was …
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Suicidal Ideation and Treatment-Resistant Depression: Clinical Endophenotype Characterization and Exploration of Novel Brain Stimulation Interventions
… Given treatment limitations of SI in TRD, novel interventions paired with an improved understanding of the neurobiology of SI are needed. In this thesis I explore the clinical phenotype of the overlap of TRD and SI through a retrospective analysis of the largest clinical trial in …
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The relationship between resilience, anxiety and depression among university students
… demand for student mental health services, novel interventions to building resilience is necessary.
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Parent perspectives of at-home cognitive intervention for preschoolers with Down syndrome
… of EF, however there are few cognitive interventions designed for young developmental ages. Parent-mediated interventions (PMIs) are emerging as an effective and scalable intervention approach for clinical populations. PMIs require ongoing parent engagement, and therefore, it is critical …
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Hypoxia Mediated Downregulation of Mirna Biogenesis Leads to Increased Tumor Progression
… and clinical patient samples, we demonstrate novel deregulatory mechanisms involved in Dicer and Drosha downregulation under hypoxia. Data from deep sequencing of normoxia and hypoxia treated cells demonstrate clear effect of this downregulation on miRNA maturation. Collectively, we show …
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Neuroplasticity and chronic low back pain: an investigation into altered tactile discrimination, body schema and motor function.
… altered alongside motor function impairments. Novel interventions to reverse these impairments coincide with reductions in pain intensity and perception. CLBP shares some characteristics with PLP and CRPS so it is plausible that novel interventions may improve CLBP outcomes. However, for …
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Designing for Deep Engagement
… modern society. In this thesis, I present four novel interventions to promote states of deep engagement. Evaluating whether one of these interventions has a meaningful impact on flow state is difficult to do. The bulk of my work, then, focuses on the methodological challenges of flow state …
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Dendritic cell regulation of immunity to Leishmania donovani
… is critical for the development of effective novel interventions. Phenotypic and functional analysis of CD11chi conventional dendritic cell subsets (cDCs) revealed widespread alterations as a result of chronic infection in the murine spleen. cDCs displayed a limited capacity for costimulatory …
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Identify the regulatory roles of intestinal secretory cell lineages during gut inflammation
… cells (EECs), in colonic inflammation, revealing novel cellular and molecular dynamics. The initial study utilized IEC-specific Hnrnp I knockout mice to demonstrate significant upregulation of pro-inflammatory cytokines such as Il1β, Cxcl1, and Ccl2. This animal model was thus validated in …
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Enabling the in vitro study of long noncoding RNAs to understand their role in Plasmodium falciparum
… gene regulation will inform the development of novel interventions for the control and eradication of malaria, which remains a serious global health concern.
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EEG Features of Working Memory Impairment in Alzheimer’s Dementia and Mild Cognitive Impairment
… MCI and AD and may help guide the development of novel interventions in the future.
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Monitoring Hand Use and Hand Role of Stroke Survivors at Home Using Egocentric Video
… is essential to measuring the ultimate impact of novel interventions after stroke. Wearable technologies have been used to capture upper limb use ratios outside of clinical environments, however, wrist-worn devices measure arm use rather than hand use, and finger-worn devices may interfere with …
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Promoting the mental health, wellbeing, and resilience of postgraduate researchers: An institutional perspective
… diverse prevalence rates. Several small-scale interventions promoting positive mental health have been conducted within universities nationally. However, these interventions tend not to be grounded in psychological theory, seldom involve students in their production, and often lack …
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Gender Stereotypes and Interventions Targeting Gender Stereotypes
… perpetuated by gender stereotypes, psychological interventions targeting gender stereotypes may be an important and effective approach. Thus, this doctoral research (1) examines the effectiveness of novel interventions designed to increase discernment of gender stereotypes in STEM and (2) aims to …
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Creatine Monohydrate Supplementation Effects on Oxidative Stress and Blood Flow in Older Adults with Overweight/Obesity
… with rates of CVD so high it is crucial to find novel interventions to reduce the risk of CVD. Creatine monohydrate (CM), a popular performance supplement, has shown promise in reducing ROS concentrations and enhancing blood flow. Therefore, the aim of the dissertation is twofold, first to …
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Surf Therapy for Children and Young People: A Systematic Literature Review of Qualitative Mental Health and Well-Being Outcomes. Exploring the Impact of Adaptive Surfing on the Mental Health and Well-Being of Children and Young People: A Multiperspectival Interpretative Phenomenological Analysis
… there is a growing drive towards developing novel interventions and prevention strategies tailored to CYP. Surf therapy is gaining recognition as a potential mental health and well-being intervention for CYP, with anecdotal evidence suggesting benefits for CYP across various presentations. …
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Intragastric Mechanical Systems for Dysmotility Diagnosis and Obesity Treatment
… development and electronic underpinnings of novel interventions that address both diagnostic and therapeutic unmet needs. Clinical evaluation of GI motility is currently limited to radiographic and nuclear methods that provide information on gastric emptying rate. While high-resolution …
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3D Analysis Of The Hip Joint For The Prediction Of Osteoarthritis
… predict osteoarthritis development is limiting. Novel biomarkers for clinically relevant hip osteoarthritis are needed particularly methods to identify patients who are destined for total hip replacement (THR) surgery and who might benefit from novel interventions. The chosen techniques studied …
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