Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 75 for “"noradrenaline"”.
-
The effects of the noradrenaline reuptake inhibitor atomoxetine on circadian rhythms in mice.
Circadian rhythms are patterns in behavioural, physiological and many others parameters that recur approximately every twenty four hours. Dysfunction of the circadian system is being linked to a number of common illnesses. The psychiatric condition Attention Deficit/Hyperactivity Disorder (ADHD) …
-
The diffusion and metabolism of noradrenaline in the artery wall / by Raymond Gregory Morris
Typescript (photocopy)
-
The stereoselective synthesis of iodinated analogues of reboxetine: new imaging agents for the noradrenaline transporter
The noradrenaline reuptake transporter is located on the pre-synaptic membrane of noradrenic neurons. Its main function is to terminate the action of the neurotransmitter noradrenaline by reuptake back into the nerve terminal. Changes in the function and density of the noradrenaline reuptake …
-
Stress-induced relapse to cocaine seeking in the rat : contributions of central nervous system corticotropin-releasing factor and noradrenaline
… corticotropin-releasing factor (CRF) and noradrenaline (NE), in stress- and cocaine-induced relapse to cocaine seeking, using an animal model of relapse. Rats were allowed to self-administer cocaine (0.5 or 1.0 mg/kg/infusion, i.v.) for 3 hours daily for 10-14 days and were then put on an …
-
Encoding and Processing of Accessory Olfactory System Odorants
… system, and this processing can be regulated by noradrenaline and other neuromodulators. Despite years of targeted research, there are only a few known ligands for this system limiting our ability to understand how odorants are processed. Part of my thesis has focused on the discovery of novel …
-
Efficacy and safety of serotonin reuptake inhibitors (SSRI) and serotonin noradrenaline reuptake inhibitors (SNRI) for children and adolescents with anxiety disorders: A systematic review and meta-analysis
… in children and adolescents. Selective serotonin noradrenaline reuptake inhibitors (SNRIs) have also been proven to be effective. This study conducts a systematic review and meta-analysis of the literature to assess the efficacy of SSRI and SNRI treatment in comparison with various control …
-
The effects of metformin on the vascular system
… were contacted with increasing concentrations of noradrenaline (10-9M, 10-8M, 10-7M, 10-6M) in the absence and presence of metformin. Maximally contracted tissue was then relaxed using increasing acetylcholine concentrations (10-9M, 10-8M, 10-7M, 10-6M). Meformin increased the sensitivity of the …
-
Catecholamine physiology in the sheep
… after 90 minute infusions of 1-dopa, dopamine, noradrenaline and adrenaline. A 2-compartmental pharmacokinetic model of 1-dopa plasma dynamics was constructed and the half-lives of the fast and slow decay curves determined. Estimation of the half-lives of dopamine, noradrenaline and adrenaline …
-
Investigation into the Vasomotor Signs and Symptoms of the Menopause
… vas deferens to transmural stimulation to noradrenaline and to potassium chloride. This suggested a direct action of 178-oestradiol upon the smooth muscle. Furthermore, 17B-oestradiol, given in a dose which is considered physiological, increased the pressor responses of the female pithed …
-
Antinociceptive actions of descending catecholaminergic tracts on dorsal horn somatosensory neurones
Ionophoretically-applied dopamine and noradrenaline selectively inhibited the nociceptive responses of multireceptive somatosensory dorsal horn neurones, whilst non-nociceptive responses, spontaneous activity and activity evoked by an ionophoretically-applied excitatory amino acid, DL-homocysteic …
-
Thermoreception, thermoregulation and the early thermal environment
… and altered response to intrahypothalamic noradrenaline injection). The present study investigated the role of the thermal environment in the development of thermoregulatory function by studying the performance of the intact thermoregulatory system and components thereof at different levels …
-
Cognitive impairment: quantification and possibilities for pharmacological treatment
… including acetylcholine, dopamine, and noradrenaline. Importantly, these functions are susceptible to pharmacological intervention with drugs such as physostigmine, modafinil, and atomoxetine. In order to explore the nature of a variety of forms of cognitive impairment, which were …
-
Single nephron structure and function, and renal effects of catecholamines in the dogfish, Scyliorhinus canicula
… Plasma levels of the catecholamines adrenaline, noradrenaline and dopamine were determined in resting fishes, and following stress induced by MS222 (Tricaine methane sulphonate) anaesthesia and surgery. 7. Infusion of adrenaline increased systolic and diastolic systemic blood pressure in …
-
The effect of cis-5,8,11,14,17-eicosapentaenoic acid upon the contractile mechanisms linked to calcium influx and the mobilisation of intracellular calcium in aortic smooth muscle
… muscle cells to the vasoactive agents KCl and noradrenaline. The latter effect was likely caused by reducing calcium influx through receptor-operated channels, supporting a recent suggestion by Asano et al (1997). Consistently, EPA decreased noradrenaline-induced contractures in aortic tissue, …
-
ΑΛΛΗΛΕΠΙΔΡΑΣΗ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΦΑΡΜΑΚΩΝ ΠΟΥ ΔΡΟΥΝ ΣΤΟΥΣ ΥΠΟΔΟΧΕΙΣ ΤΩΝ ΚΑΤΕΧΟΛΑΜΙΝΩΝ ΚΑΙ ΦΑΡΜΑΚΩΝ ΠΟΥ ΕΠΗΡΕΑΖΟΥΝ ΤΗΝ ΔΙΑΚΙΝΗΣΗ ΑΣΒΕΣΤΙΟΥ ΣΕ ΑΠΟΜΟΝΩΜΕΝΗ ΑΟΡΤΗ ΕΠΙΜΥΟΣ. ΔΙΕΡΕΥΝΗΣΗ ΤΗΣ ΔΡΑΣΕΩΣ ΤΗΣ ΑΜΙΩΔΑΡΟΝΗΣ
… MORE SPECIFICALLY , IT STUDIES THE EFFECT OF NORADRENALINE, POTASSIUM CHLORIDE, SEROTONIN, AND OF PROSTAGLANDIN F2A ON THE PREPARATION, WHILE SIMULTANEUSLY, IT EXAMINES THE VASODILATOR ACTION OF AMIODARONE AND ITS INTERACTION WITH THE USED VASOCONSTRICTIVE AGENTS, BOTH IN CALCIUM- CONTAINING …
-
The role of intracellular Ca2+ in the arrhythmogenic activity of pulmonary vein cardiomyocytes
… when the external Ca2+ concentration was raised. Noradrenaline also increased the frequency of the spontaneous Ca2+ transients; however, synchronous Ca2+ transients, like those that could be evoked by electrical field stimulation, were not observed.As spontaneous Ca2+ transients are due to Ca2+ …
-
The evaluation of targeted radionuclide therapies and radio sensitising agents in malignant melanoma
… therapy via transfection invitro with noradrenaline transporter (NAT) and via gene delivery in vivo withthe HSV1716/NAT vector. • To screen novel DNA repair and IKKβ Inhibitors in combination with X-Ray radiation to determine suitability for future targeted radiotherapy/drug combination …
-
Psychological, cardiovascular and haematological aspects of the type A behaviour pattern in relation to coronary heart disease
… diastolic blood pressure, plasma adrenaline and noradrenaline. They also demonstrated the faster platelet aggregation (although percentage aggregation decreased similarly for both groups), together with the greater increase in the anticoagulant, antithrombin III. The complexity of these …
Page 1 of 4