Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"nontuberculous mycobacteria"”.
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Isolation and molecular characterization of Non-Tuberculous Mycobacteria of Public Health significance from Humans and water in Namwala Districts of Zambia
… infections due to environmental Non-tuberculous Mycobacteria are increasingly becoming a public health threat due to the Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome pandemic. In Zambia, Non tuberculous Mycobacteria are gaining recognition as pathogens of public health …
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Isolation and molecular characterization of Non-Tuberculous Mycobacteria of Public Health significance from Humans and water in Namwala Districts of Zambia
… infections due to environmental Non-tuberculous Mycobacteria are increasingly becoming a public health threat due to the Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome pandemic. In Zambia, Non tuberculous Mycobacteria are gaining recognition as pathogens of public health …
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Adherence and Biofilm Formation of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium abscessus in household plumbing
Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and found in drinking water distribution systems and household plumbing. They are opportunistic pathogens of humans, causing lung disease. Their ability to adhere and form biofilm is attributed to a waxy, lipid-rich, cell envelope. …
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Identifying cross-species regimens for the treatment of rapid-growing and slow-growing nontuberculous Mycobacterium pulmonary infections
Nontuberculous mycobacteria (NTM), especially Mycobacterium avium and Mycobacterium abscessus, are increasingly significant causes of chronic pulmonary disease. Current treatments are lengthy and often ineffective, with culture conversion often below 60% in refractory patient populations. Due to …
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Targeting infectious species by Structure-guided Fragment-based Drug Discovery and in silico approach
… a rapidly growing multidrug-resistant species of nontuberculous mycobacteria (NTM) in addition to the well-characterised highly virulent species of ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and …
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Characterization of opportunistic Pathogens in Drinking Water Supplied by Private Wells
… spp., Mycobacterium avium (the most commonly nontuberculous mycobacteria associated with disease), and Naegleria fowleri in private wells with recent history of flooding (i.e., Hurricanes Harvey and Irma in 2017, or the Great Louisiana Floods in 2016, extending to Texas, Florida, and …
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Assessing the Potential of Granular Activated Carbon Filters to Limit Pathogen Growth in Drinking Water Plumbing Through Probiotic Versus Prebiotic Mechanisms
Legionella pneumophila (Lp) and nontuberculous mycobacteria (NTM) are opportunistic pathogens that can be transmitted via drinking water, when tiny droplets containing the bacteria are aerosolized and inhaled during activities such as showering. The resulting respiratory illnesses, Legionnaires’ …
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Evolutionary Genomics of Cystic Fibrosis and Nosocomial Pathogens of the Mycobacterium abscessus species complex
The $\textit{Mycobacterium abscessus}$ species complex (MABSC) consists of three subspecies, $\textit{M. a. abscessus}$, $\textit{M. a. massiliense}$ and $\textit{M. a. bolletii}$. All three of these subspecies are capable of causing opportunistic pulmonary and skin and soft tissue infections in …
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Residential Exposure to Non-tuberculous Mycobacteria: Sources and Associations with Pulmonary Disease
The human health impacts of non-tuberculous mycobacteria (NTM) in home environments remain poorly understood. To better understand the association between NTM colonization of POU sources in homes and MAC pulmonary disease (MAC PD), we continued a case-control study of Washington and Oregon …
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Inhibition of enzymes from mycobacteria using fragment-based approaches
… of fragment-based approaches for two essential mycobacterial target proteins, fumarate hydratase (fumarase) from Mycobacterium tuberculosis (Mtb) and tRNA (m1G37) methyltransferase (TrmD) from Mycobacterium abscessus (Mab). With Mtb fumarase a high-throughput screening (HTS) hit was used to …