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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 13 of 13 for “"nonstructural proteins"”.

  1. Of Mice and Men and Cattle: Functions of the Pneumovirus Nonstructural Proteins NS1 and NS2 in Interferon Escape

    Bossert, BirgitLudwig-Maximilians-Universität

    … of pneumoviruses is the presence of two unique nonstructural protein genes, NS1 and NS2. We show that both BRSV NS proteins are necessary and sufficient to mediate IFN resistance. This function can also be transferred to another, unrelated virus, Rabies virus. The mechanism of IFN resistance is …

    lmu-germany Repository record

  2. Molecular characterization of novel soybean-associated viruses identified by high-throughput sequencing

    Yasmin, TubaUniversity of Illinois at Urbana-Champaign2016

    … of the first ORF showed similarity to structural proteins, of members of the invertebrate-infecting Dicistroviridae and the sequence of the second ORF which is a nonstructural proteins lack affinity to other virus sequences available in GenBank. The presence of separate ORFs for the structural and …

    uiuc Repository record

  3. Bacteriophage Sp10 Infection of Bacillus Subtilis

    Katt, Wayne Charles

    … versus uninfected cells. While no viral-coded nonstructural proteins were detected with this technique, five bands were assigned as viral structural proteins as evident in phage-infected cells.

    mo-state Repository record

  4. Genetic and Biochemical Analyses of the Flaviviridae Capsid Proteins

    Murray, Catherine Lucy

    … lipid membrane outfitted with envelope glycoproteins. The process of virion morphogenesis is not well understood, but the presumed involvement of numerous viral and cellular components makes it an attractive target for novel therapeutic drug design. To investigate the early events of …

    rockefeller Repository record

  5. A reverse genetics study of the Human Coronavirus 229E ADP-ribose-1"-phosphatase

    Dammann, SabineQueen's University Belfast2011

    … This involves the expression of two large polyproteins, pp1a and pp1ab, that are autoproteolytically processed to produce nonstructural proteins (nsp) 1 to 16. In this study, enzymatic activities associated with Human coronavirus 229E (HCoV-229E) nsp3 were characterised. <br/><br/>First, …

    qu-belfast Repository record

  6. Aphid Transmission, Replication, and Transcription of BYDV -Pav -Il and Genome Organization of RhPV

    Moon, Jae SunUniversity of Illinois at Urbana-Champaign2015

    … library was screened to identify aphid proteins that interact with the BYDV-PAV-IL capsid proteins using the yeast two-hybrid system. Seven clones activated the expression of the reporter genes, supposedly by interacting with capsid proteins of BYDV-PAV, but complementation tests …

    uiuc Repository record

  7. γδ T CELLS MEDIATE PROTECTIVE IMMUNE RESPONSES INDUCED BY EILV/CHIKV, A CHIMERA VACCINE CANDIDATE, AGAINST CHIKUNGUNYA INFECTION

    Rodriguez, Leslie 1996-The University of Texas Medical Branch at Galveston2025

    … An EILV/CHIKV chimera that contains the nonstructural proteins of EILV and the structural proteins of CHIKV has previously shown to protect against wild-type (WT) CHIKV challenge in rodents and non-human primates. The mechanism of the vaccine-induced protection remains unknown. γδ T cells …

    utmb Repository record

  8. Mutational analysis of the West Nile Virus NS4B protein

    Jason Alan WickerThe University of Texas Medical Branch2007

    … proteases to produce three structural and seven nonstructural proteins. The NS4B protein is a small hydrophobic protein approximately 27kD in size that is hypothesized to participate both in the viral replication complex and evasion of host innate immune defenses. The objective of this …

    utmb Repository record

  9. Identifizierung und Charakterisierung von Interaktionen der Nichtstrukturproteine NS1 und NS2 des Respiratorischen Synzytialvirus mit Proteinen der Wirtszelle

    Wolff, MichaelLudwig-Maximilians-Universität

    … Respiratory Syncytial Virus (RSV) encode two nonstructural proteins, NS1 and NS2. These two proteins cooperatively mediate type I interferon resistance and prevent induction of interferon in infected cells. Interactions of NS1 and NS2 proteins in every combination were shown by using the …

    lmu-germany Repository record

  10. The characterisation of aspects related to the single stranded RNA binding ability of African horsesickness virus nonstructural protein NS2

    University of Pretoria2006

    … segments that encode seven structural and four nonstructural proteins. AHSV nonstructural protein NS2, encoded by segment eight, is a single stranded RNA (ssRNA) binding protein. The formation of viral inclusion bodies (VIBs) as well as the selection and condensation of the ten different virus …

    pretoria Repository record

  11. Innate immune evasion and interferon antagonism by porcine epidemic diarrhea virus

    Zhang, QingzhanUniversity of Illinois at Urbana-Champaign2018

    … suppressed during PEDV infection, and of 16 PEDV nonstructural proteins (nsps), nsp1, nsp3, nsp7, nsp14, nsp15, and nsp16 were found to inhibit the IFN-β and IRF3 promoter activities. The sole accessory protein ORF3 and the envelope (E), membrane (M), and nucleocapsid (N) proteins were also …

    uiuc Repository record

  12. Structure-guided insights into the functions of CHIKV nsP2

    Wang, Sainan2024

    tartu

  13. Mechanism of Pathogenesis and Replication of an Avian Strain of the Hepatitis E Virus in a Chicken Model

    Billam, PadmaVirginia Tech2007

    … were observed in ORF1, the region coding for the nonstructural proteins. Six unique non-silent mutations were identified in the capsid-encoding ORF2 region and the ORF3 had four non-silent mutations. Phylogenetic analysis based on full-length genomic sequence revealed that the avirulent strain is …

    vt Repository record