Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"nonhuman primates"”.
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Behavioral Mechanisms of Δ9-THC in Nonhuman Primates
… established in one laboratory using New World primates (squirrel monkeys). In Chapter 2, THC and the synthetic cannabinoid agonist CP55,940 were made available for SA in Old World monkeys, a species more closely related to humans, by using similar parameters deemed successful in squirrel …
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Network theory analysis of ethanol self-administering nonhuman primates
… this methodology to animal models, particularly nonhuman primates (NHPs). NHPs are considered a powerful translational tool that bridge basic science and clinical studies. They are also useful because the morphology of their cerebral cortex is similar to humans. In this work, a network processing …
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Salivary Biomarkers of Acute Stress and Insulin Sensitivity in Nonhuman Primates
Saliva may be a superior matrix for physiologic measurement because it is noninvasive and allows short-term assessment. Salivary alpha-amylase (sAA) is a novel biomarker of stress in humans, has implications with diabetes, and could be a new tool for improving health and welfare in zoo animals. The …
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Clonotypic Analysis of CMV-Specific CD4+ T Cells in Human and Nonhuman Primates
… of a protective CD4+ T cell memory response in primates using CMV as a model viral pathogen. First, we characterized the clonotypic hierarchy of an established CMV-specific CD4+ memory T cell response in human subjects and Rhesus macaques (RM). In both we found that long-term CD4+ memory …
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Comparative Studies of Numerical Cognition in Nonhuman Primates: From Numerical Comparison to Arithmetic
<p>There is a long-standing claim that humans and nonhuman primates share an evolutionarily ancient system of nonverbal number representation. By and large, the focus in the field has been on providing existence proofs of numerical competence in wide-ranging taxa or using individual species as …
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Origins of numerical concepts : a comparative study of human infants and nonhuman primates
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1997.
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NONHUMAN PRIMATES AS A TRANSLATIONAL MODEL OF ENDOMETRIOSIS AND ITS EFFECTS ON WOMEN'S HEALTH
… processes. The project objectives were to use a nonhuman primate (NHP) model of endometriosis to address gaps in knowledge surrounding tissue macrophage function, endometriosis and eutopic endometrium metabolism, and systemic iron metabolism. The overall hypothesis for this research was that …
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A Multivariate Morphometric Study of Cranio-Vertebral Shape Changes in Man and Various Nonhuman Primates
Made available in DSpace on 2014-12-14T05:35:17Z (GMT). No. of bitstreams: 1 7726740.pdf: 12018105 bytes, checksum: a63c9b590ef71e0c9a4d92c1d2a06621 (MD5) Previous issue date: 1977
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How Researchers Address Ethical Concerns Regarding Habituating Nonhuman Primates: Results of a Survey and Suggestions for Future Practice
… perceptions regarding the habituation of wild nonhuman primates. I distributed an online survey to primatologists and received 406 responses, 286 of which were used in data analysis. I used two sets of six-scale Likert scoring questions to determine respondents’ perceived ethical concerns and …
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Response of Three Species of Monkeys to Caregiver Use of Species-Typical Behavior
… addressing psychological well-being of captive nonhuman primates, social environment should be considered. Chimpanzees, gorillas, New World monkeys, and Old World monkeys responded positively to interactions with caregivers. Some species showed increased affiliative behaviors and decreased …
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Brain microelectrode array systems
… for intracortically recording brain activity in nonhuman primates, were developed and explored. Wire electrical discharge machining (EDM), chemical etching, micromilling, parylene deposition, and laser ablation were some of the processes employed to create distinctive microstructures with fine …
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Analysis of FY Promoter and Hepatocystis Load in South African Vervet Monkeys (Chlorocebus Aethiops)
… variation at the FY gene, a homologous area in nonhuman primates, impacts resistance to <em>Hepatocystis</em> and <em>Plasmodium </em>infection in some nonhuman primates (Schmidt et al., 1977; Tung et al., 2009; Butcher et al. 2010). The current study looks at the FY promoter region in vervet …
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The Effect of Sound on Captive Chimpanzees (<i>Pan troglodytes</i>)
… psychological effects on humans, but effects on nonhuman primates are not as well understood. Captive chimpanzees are exposed to markedly different acoustic environments than their wild counterparts. This study assessed the organic soundscape of a chimpanzee sanctuary, the Fauna Foundation, in …
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Empirical constraints on the evolutionary origins of music
… with a focus on comparative experiments in nonhuman animals. A series of studies in nonhuman primates explores whether they have preferences for sounds that might be related to music perception in humans. A second set of studies explores whether preferences for music can be instantiated in …
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Description of interactions of Ebola virus with a putative reservoir species using next-generation sequencing
… a severe, often fatal disease in humans and nonhuman primates. Recently, EBOV has caused two very large outbreaks, one of which is ongoing in the Democratic Republic of the Congo. Bats are the likely reservoir of EBOV, but little is known of their relationship with the virus. Next-generation …
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On Immunological Imprinting
… were investigated in imprinted humans and nonhuman primates after SARS-CoV-2 variant exposures. Although variant responses predominantly arose from imprinted memory, de novo variant type-specific responses were identified in several individuals. As a primary exposure, variants were …
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Determining the Innate and Adaptive Immune Responses to Vesicular Stomatitis Virus Vaccine Vectors
… many different antigens. Studies in mice and nonhuman primates have demonstrated efficacy against several pathogens. A novel strategy to enhance VSV as an effective vaccine is to engineer vectors that induce innate immune mechanisms. We have generated an improved VSV vaccine vector that …
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Compassion Fatigue and Satisfaction in U.S. Army Laboratory Animal Medicine Personnel
… compassion satisfaction included working with nonhuman primates, difficulty working with primary investigators, loneliness, and euthanasia distress. These findings can inform future research efforts to explore compassion fatigue in animal research environments, as well as initiatives for …
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Sylvatic dengue: evolution, emergence, and impact on human health
… includes a sylvatic, enzootic cycle between nonhuman primates and arboreal mosquitoes of the genus Aedes, and an urban, endemic/epidemic cycle between Aedes aegypti, a mosquito with larval development in peridomestic water containers, and human reservoir hosts. All 4 serotypes of endemic DENV …
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Engineered microneedles for transcutaneous vaccine delivery
… testing of these vaccine patches in mice and nonhuman primates demonstrated equivalent immunogenicity compared to parenteral injection, eliciting strong systemic and disseminated mucosal CD8' and CD4* T cell responses to a model HIV antigen. These cellular responses were correlated with a …
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