Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 37 for “"nonhuman primate"”.
-
Pluripotency and patterning in nonhuman primate embryogenesis
… of this property of the early embryo. However, primate embryogenesis differs in anatomical architecture, developmental timing, and molecular configuration. Obvious ethical considerations limit human embryo research, thus nonhuman primates offer an opportunity to unravel primate-specific features …
-
Segmentation of Subcortical Structures from Nonhuman Primate MRI
… analysis of subcortical structures within the nonhuman primate can potentially have a profound impact on studying the relationship between volumetric characteristics and alcohol dependencies. Image segmentations have been widely used in quantifying structural information. There are a variety of …
-
The Effects of Chronic Ethanol on GABA Receptors in the Nonhuman Primate Brain
… In a translational approach, we utilized a nonhuman primate model of chronic ethanol self-administration to investigate total GABAA, alpha1 and alpha 4/6 subunit-containing receptor binding density in a variety of cerebral cortical regions and the cerebellum. Ethanol induces region and layer …
-
Neurological Effects of Low-Level, Chronic Domoic Acid Exposure in a Nonhuman Primate Model
… chronic DA exposure during pregnancy in a nonhuman primate model (Macaca fascicularis). Early results from this study demonstrated that daily, oral exposure to 0.075 to 0.15 mg DA/kg/day for up to two years, induced symptoms in adults that were manifested as intention tremors (Burbacher et …
-
FUNCTIONAL, STRUCTURAL, CELLULAR, AND MOLECULAR CARDIAC RESPONSES IN NONHUMAN PRIMATE MODELS OF MENOPAUSE AND RADIATION EXPOSURE
Physiologic estrogen loss (menopause) and ionizing radiation exposure are gaining attention as drivers of cardiac remodeling leading to heart failure, particularly heart failure with preserved ejection fraction (HFpEF). Myocardial fibrosis appears to be a shared pathologic feature of both …
-
EFFECTS OF ALCOHOL AND ACAMPROSATE, AN ALCOHOL USE DISORDER TREATMENT, ON NONHUMAN PRIMATE BEHAVIOR AND MEMORY
Alcohol use disorder (AUD) is a major issue facing the population both domestically and abroad. The repeated use of alcohol impairs various behavioral and cognitive functions such as attention and memory and disrupts normal communications between brain regions. These disruptions in communication …
-
ESTROGEN, VASCULAR INFLAMMATION, AND INTERLEUKIN-17 IN RELATION TO ATHEROSCLEROSIS IN A FEMALE NONHUMAN PRIMATE MODEL
The role of T helper 17 (Th17) cells and interleukin-17A (IL-17A), a signature pro-inflammatory cytokine for Th17, in atherosclerosis is unknown. Postmenopausal estrogen therapy (ET) mediates atheroprotection in part through anti-inflammatory effects; however, the effects of ET on Th17 cells and …
-
Dietary Soy Protein Isoflavonoid Effects on the Reproductive Tract of the Nonhuman Primate and Neoplastic Human Prostate Gland
Epidemiologic studies have revealed marked disparities in prostate cancer incidence throughout the world. Prostate cancer incidence is estimated to be 10 to 60 times lower in Asian men living in their country of origin when compared to African American and Caucasian American men. The precursor …
-
The nature of habits in the nonhuman primate : the formation of sequences of eye movements and neural activity in the frontal eye field
The nature of habits, their formation, expression, and underlying causes have been pondered for centuries. Early definitions, still in use today, posited that habits are actions associated with outcomes that, when repeated, become stimulus-response associations that can be performed automatically, …
-
The Characterization of Several Intestinal Spirochetes of Animal Origin
… (1) to isolate an intestinal spirochete from a nonhuman primate and to characterize it along with several other intestinal spirochetes from a pig, dog, mouse, opossum, and gibbon on the basis of structural and selected biochemical characters, (2) to evaluate these properties using numerical …
-
The Functional Role of Anatomical Feedback Connections In Visual Attention
… attention, have traditionally been studied in nonhuman primate models, the available methodologies have made it difficult to examine. On the other hand, work with mouse models has utilized modern methods, and studies have suggested that other top-down signals may be transported by anatomical …
-
Re-Evaluating Captive Chimpanzee “Dominance”: Dominance Hierarchy and Chimpanzee-Caregiver Relationships at Chimpanzee Sanctuary Northwest
… analyzes dominance relationships in two nonhuman primate groups with novel methods, possible correlations between dominance and testosterone, and uncovers the prominent connection of caregivers to captive chimpanzee social networks. Chapter I addresses current and past variability in …
-
Effects of Chronic Selective Serotonin Reuptake Inhibitor Use on Carotid Artery Atherosclerosis
… associated risk factors using a translational nonhuman primate model of depression.
-
The Cellular and Molecular Determinants of Hippocampus Size in a Female Monkey Model of Depression
… Detailed evaluations of the hippocampus in a nonhuman primate model of depression in which the neurobiology more closely resembles that of humans while still allowing experimental control over potential confounds would help clarify these issues and further elucidate the mechanisms responsible …
-
Ecological and Anthropogenic Influences on a Sentinel Species' Gut Microbiome
<p>Central and South American primates face augmented challenges due to increased rates of forest fragmentation. Among these challenges are implications on the nonhuman primate gut microbiome. Wild Argentine black and gold howler monkeys (<em>Alouatta caraya</em>) are listed as “least concern” with …
-
Ethnoprimatology of Urban Cebus Yuracus: An evaluation of Human-non-human interactions and local perceptions in Misahualli, Ecuador
… ethnoprimatological study focuses on the human-nonhuman interactions and the perceptions of the local people about the capuchin group. Behavioral interactions were examined using all-occurrence sampling, and the local perceptions of the Misahuallí people were assessed using semi-structured …
-
Pictorial Primates: A Search for Iconic Abilities in Great Apes
… used extensively in psychological experiments on nonhuman primate perception, categorisation, etc. They are also used in everyday interaction with primates, and as pure entertainment. But in what ways do primates understand iconic artefacts? What implications do these different ways have for the …
-
NONHUMAN PRIMATES AS A TRANSLATIONAL MODEL OF ENDOMETRIOSIS AND ITS EFFECTS ON WOMEN'S HEALTH
… processes. The project objectives were to use a nonhuman primate (NHP) model of endometriosis to address gaps in knowledge surrounding tissue macrophage function, endometriosis and eutopic endometrium metabolism, and systemic iron metabolism. The overall hypothesis for this research was that …
-
Interactive Effects of Bazedoxifene acetate and Conjugated Equine Estrogens on the Breast and Reproductive Tract of Postmenopausal Monkeys
… of CEE on the vaginal mucosa. As part of a nonhuman primate translational trial evaluating the global benefit to risk profile of BZA+CEE and BZA alone, we found that the addition of BZA to CEE significantly antagonized the stimulatory actions of CEE on breast and endometrial Ki67 …
-
GENETIC CHARACTERIZATION OF THE ST. KITTS-ORIGIN VERVET MONKEY (CHLOROCEBUS AETHIOPS SSP.) AS A MODEL OF POLYGENIC OBESITY
… the St. Kitts-origin vervet monkey as a nonhuman primate (NHP) of polygenic obesity, the human ortholog vervet TNF gene and flanking regions were sequenced and genotyped from 265 monkeys in a closed, pedigreed colony. This revealed a total of 11 single nucleotide polymorphisms (SNPs), and …
Page 1 of 2