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Showing 1 to 4 of 4 for “"nonactin"”.
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The Use of Natural Product Substrates for the Synthesis of Libraries of Biologically Active, New Chemical Entities
… compounds 72 and 71, which are derived from nonactin, a biologically active natural product. Nonactin 40, an ionophore macrotetrolide antibiotic that is produced by Streptomyces griseus ETH A7796, is an ideal candidate for the synthesis of new antimicrobial drugs. This secondary metabolite is …
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The Use of Natural Product Substrates for the Synthesis of Libraries of Biologically Active, New Chemical Entities
… compounds 72 and 71, which are derived from nonactin, a biologically active natural product. Nonactin 40, an ionophore macrotetrolide antibiotic that is produced by Streptomyces griseus ETH A7796, is an ideal candidate for the synthesis of new antimicrobial drugs. This secondary metabolite is …
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Synthesis and Structure Activity Relationship Studies of a Natural Product-Derived Compound Library
… library derived from the natural product, nonactin. A preliminary library was previously synthesized by Phillips that yielded two lead compounds that were the starting points for this work. The lead compounds were systematically modified over four iterations of a Structure Activity …
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Synthesis and Structure Activity Relationship Studies of a Natural Product-Derived Compound Library
… library derived from the natural product, nonactin. A preliminary library was previously synthesized by Phillips that yielded two lead compounds that were the starting points for this work. The lead compounds were systematically modified over four iterations of a Structure Activity …