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Showing 1 to 1 of 1 for “"non-processive unwinding"”.
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Direct observation of XPD helicase base-pair stepping and regulation by RPA2
… of the genomic integrity. First, we examined DNA unwinding by XPD helicase in isolation to understand the basic physicochemical process of DNA base pair (bp) separation. We demonstrated that monomeric XPD unwinds duplex DNA in single base-pair steps, yet is non-processive, unwinding for short …