Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"non-oncogene"”.
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Taspase1 is a Non-oncogene Mediator of Tumorigenesis and Maintenance
The clinical success of oncogene-targeted therapies substantiates the continued reliance of certain cancers upon the continued function of apical oncogenes involved in its genesis--a phenomenon known as "oncogene addiction." Though this shift from non-targeted, cytotoxic therapies offers new hope …
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Identification and Characterization of Potential Novel Targets in Thyroid Carcinoma: Evidence of Non-Oncogene Addiction Unveiling Tumor Cell Vulnerabilities
… intervention, our laboratory faced the “non-oncogene addiction” (NOA) paradigm, which asserts that the tumorigenic state relies on the activity of genes that are essential to support the phenotype of cancer cells but not required to the same degree for normal cell viability. By screening …
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Role of Nudix-Hydrolase ASMTL in Modulating Mitochondrial Biogenesis of Cancer Cells
… like ASMTL, which prevent incorporating the non-canonical nucleotides into newly synthesized DNA by removing them from the nucleotide pool, thereby relieving cancer cells from proliferative stress-induced mutations and apoptosis, representing an attractive target for anti-cancer chemotherapy. …