Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"non-inflammatory"”.
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The Effect of Aberrant Inflammation During Pregnancy on Subsequent Risk of Maternal Metabolic Disease Development
Inflammatory pregnancy complications are linked to an increased development of metabolic disease in mothers and their offspring. Previous studies from our lab have shown the development of risk factors for disease development following pregnancy complications. It is thought that pregnancy …
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Characterisation of the HIV inhibitory activity of vaginal lactobacilli isolates from young South African women at high risk of HIV acquisition
… do not exist. BV is associated with upregulated inflammatory cytokine levels in the female genital tract (FGT), which in turn may increase HIV infection risk by recruiting and activating HIV target cells, reducing epithelial barrier function and directly promoting HIV replication. Lactobacillus …
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ΑΚΤΙΝΟΛΟΓΙΚΑ ΕΥΡΗΜΑΤΑ ΤΩΝ ΑΛΛΟΙΩΣΕΩΝ ΣΤΗΝ ΑΥΧΕΝΟ-ΙΝΙΑΚΗ ΠΕΡΙΟΧΗ ΣΕ ΑΣΘΕΝΕΙΣ ΜΕ ΡΕΥΜΑΤΟΕΙΔΗ ΑΡΘΡΙΤΙΔΑ. ΚΛΑΣΣΙΚΕΣ ΑΚΤΙΝΟΓΡΑΦΙΕΣ, ΑΞΟΝΙΚΗ ΤΟΜΟΓΡΑΦΙΑ, ΜΑΓΝΗΤΙΚΟΣ ΣΥΝΤΟΝΙΣΜΟΣ
… AND THE SPINAL CORD. IT CAN ALSO DIFFERENTIATE INFLAMMATORY FROM NON-INFLAMMATORY CHANGES, IN MORE CASES THAN CT DOES. IT IS HOWEVER INTERIOR IN VISUALISING BONE REACTIONS.
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Analysis of Periapical Biopsies Submitted for Histopathological Evaluation: A Retrospective Study
… lesions were categorized as (a) odontogenic inflammatory, (b) odontogenic non-inflammatory, (c) non-odontogenic non-neoplastic, or (d) non-odontogenic neoplastic in nature, respectively, and the prevalence of lesions in each pathologic category was determined. The correlations among …
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Regulation of Dendritic cell function by the ocular microenvironment
… in vitro model of DC function, I observed that non-inflammatory aqueous humour (AqH) inhibited DC maturation, with reduced MHC and CD86 expression, and reduced capacity to induce proliferation of allogeneic T cells, an effect which was cortisol and TGFβ2 dependent. In contrast, exposure to …
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Modulation of host NF-[k̳̳a̳p̳p̳a̳]B pathway by the Toxoplasma gondii secreted factor, GRA15
… of host immunity, toward either the classical inflammatory or the alternative non-inflammatory pathway. Using forward genetic analysis, we have isolated the secreted protein GRA 15 that is necessary and sufficient for host NF-[kappa]B activation. We find that GRA 15 activates NF-[kappa]B …
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Comparison of 18F-Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (18F-FDG PET/CT) and conventional imaging (CI) for locally advanced breast cancer staging: a prospective study from a tertiary hospital cancer centre in Western Cape
… PET/CT is useful for staging locally advanced non-inflammatory infiltrating ductal carcinoma of the breast. Use of 18F-FDG PET/CT was superior to conventional imaging in assessing metastatic mediastinal lymphadenopathy, but with a poor specificity. The use of 18F-FDG PET/CT in LABC is useful, …
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Influenza A Virus Induced Programmed Cell Death
… mechanism. Programmed cell death can be largely non-inflammatory (e.g., apoptosis) or pro-inflammatory (e.g., necroptosis). In this dissertation, I outline experiments carried out to identify the role of pro-inflammatory programmed cell death in influenza A virus clearance and pathogenesis both …
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‘Food that disagrees with me’: An exploration from a psychological perspective.
… is very individualistic. Study 2, showed that inflammatory symptoms were more frequent in the food intolerant population compared to non-inflammatory symptoms. It was also found that participants who reported being high in neuroticism and high in hypochondriasis were 20% more likely of having …
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Characterization of Biomedical and Incidental Nanoparticles in the Lungs and Their Effects on Health
… to administer therapeutic nanoparticles. Indeed, inflammatory diseases such as asthma and emphysema could potentially benefit from nanoparticle-mediated delivery. However, the lungs are also in constant contact with airborne particulate matter. Thus, harmful nanoparticles can enter the lungs and …
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Polysequence Nanomaterials for Immunomodulation
… termed glatiramoids, which promote anti-inflammatory and TH2 immune responses. We created an immunomodulatory supramolecular nanomaterial system inspired by the randomized nature of glatiramoids termed KEYA-Q11. By creating a glatiramoid-like peptide library integrated within …
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Variations in Antigen Presentation Define Regulatory T Cell formation and Activity in Vivo
… and whether Ag recognition occurs in an inflammatory environment. Recognition of a weakly immunostimulatory self-peptide was able to promote both thymic CD4+Foxp3+ Treg cell development and the formation of CD4+Foxp3+ Treg cells from CD4+Foxp3- T cell precursors in the periphery. Despite …
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The pathogenesis of murine retroviral-induced noninflammatory spongiform polioencephalomyelopathy: Neuronal degeneration is indirectly mediated by resident microglial cells
… progressive hind-limb paralysis associated with non-inflammatory spongiform lesions and motor neuron degeneration within selected nuclei of the brainstem and ventral horns of the cervical and lumbar enlargements of the spinal cord. To determine the biologic basis of ts1 MoMuLV neurovirulence, …
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The Use of Surface Cytokines as Biomarkers in B Cell Mediated Autoimmune Diseases
… RA and in the plasma of SLE patients compared to non-inflammatory OA patients indicating that TSLP may act locally in the joints of RA patients and systemically in SLE patients. These studies provide insight into the role of APRIL and TSLP in B cell mediated autoimmune diseases and provide a …
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The role of genetic alterations in the gut-joint axis of Crohn's disease and Spondyloarthropathies
… were noted in the genetic expression profile of non-inflammatory colonic biopsies of CD patients and SpA patients with chronic intestinal inflammation using array analyses. Finally, we demonstrated that the search for differential gene expression may lead to the identification of new …
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Synthesis and characterization of cationic contrast agents & imaging of articular cartilage using X-ray computed tomography and magnetic resonance
Osteoarthritis (OA) is a painful, chronic, non-inflammatory disease affecting 140 million people worldwide that alters synovial joint structure and function. OA progressively breaks down hyaline cartilage, the hydrated tissue that provides a smooth, nearly frictionless surface and distributes loads …
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Bioactive Lipids in Nociception
… TRPV1, an important downstream target for inflammatory mediators, in the phospholipase C (PLC)/TRPV1 signaling pathway. Evidence is presented for a fatty acid amide hydrolase (FAAH)-dependent fatty acid conjugation of p-aminophenol, a known acetaminophen metabolite, to form the potent TRPV1 …
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The Effect of Glucosamine Usage Combined with Non-Traditional Exercise on the Ability to Meet Self-Care Requisities for Clients with Osteoarthritis of the Knee
<p>Osteoarthritis (OA), a chronic mostly non-inflammatory disorder of the major weight-bearing joints is the most common joint disease in the United States. The knee joint is the most frequently involved in osteoarthritis. The prevalence of physician- diagnosed arthritis is estimated at 22.4 …
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Mechanically-Induced Osteocyte-Th17-Cell Signaling and Osteoclastogenesis
… While apoptosis is commonly referred to as a non-inflammatory event, inflammatory cytokines have been shown to be mediators of the bone remodeling process. To my knowledge no one has examined inflammatory cytokines in relation to fatigue induced microdamage and the targeted bone remodeling …
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Pathogenesis, presentation, and treatment of keratoconus within the United States
Keratoconus is a non-inflammatory thinning of the cornea that can lead to an irregular conical shaped protrusion generally of the lower mid-peripheral nasal or temporal hemisphere of the cornea. This degenerative disorder has no known individual cause, nor does it have a known cure. Causes have …
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