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Showing 1 to 2 of 2 for “"non-histone substrates"”.

  1. Proteome-Wide Prediction of Acetylation Substrates

    … part through posttranslational modifications of histone proteins, which are involved in disrupting chromatin contacts or by recruiting effector proteins to chromatin. Acetylation is one of the well-studied post-translational modifications that has been associated with chromatin-associated …

    rockefeller Repository record for Proteome-Wide Prediction of Acetylation Substrates (opens in a new tab)

  2. HDAC6 activity is required for efficient polarization and intracellular transport of organelles in directionally migrating cells

    Deacetylation of non-histone substrates by histone deacetylase 6 (HDAC6) has been shown to affect chemotactic invasion (e.g., Haggarty et al., 2003; Hubbert et al., 2002; Tran et al., 2007) or wound healing motility (Lafarga et al., 2012) of fibroblasts. Chemotactic invasion and wound-healing …

    columbia-diss Repository record for HDAC6 activity is required for efficient polarization and intracellular transport of organelles in directionally migrating cells (opens in a new tab)