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Showing 1 to 1 of 1 for “"non-Disjunktion"”.
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The physiological role of the two isoforms of DNA topoisomerase II in human cells
… low affinity. Consequently an increased rate of nondisjunction is observed in these cells. It is concluded that high affinity chromatin binding of topoisomerase IIalpha is essential for chromosome condensation/disjunction and that topoisomerase IIbeta does not adopt these functions. A centrosomal …