Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"nociceptive hypersensitivity"”.
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Damage-Induced Inflammation and Nociceptive Hypersensitivity In Drosophila Larvae
… model of damage-induced inflammation and pain hypersensitivity using Drosophila larvae. To study wound-induced inflammation, we generated transgenic larvae with fluorescent epidermal cells and blood cells (hemocytes). Using live imaging, we monitored the circulatory dynamics of hemocytes and …
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Investigating the Role of Insulin-Like Signaling in Paclitaxel-Induced Nociceptive Hypersensitivity using Drosophila melanogaster
… alters microtubule dynamics, is known to induce nociceptive hypersensitivity and sensory neuron damage in human patients and in Drosophila larvae. We used a modified feeding protocol to establish a genetically tractable Drosophila model of PTX-induced hypersensitivity. Larvae fed PTX exhibited …
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Investigation of chemotherapy-induced peripheral neuropathy-related behaviour in male and female ratsa role for the endocannabinoid system
… neuropathy model revealed robust somatosensory hypersensitivity to mechanical and cold, but not heat, stimuli in both sexes. These sensory alterations were of a similar magnitude in males and females and occurred in the absence of anxiety-, depression-, or cognition-related changes, indicating a …
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Two methods of biomarker discovery: applications in neuropathic pain and pharmacotherapy.
… passive bystanders, but actively contribute to nociceptive hypersensitivity in the lumbar spinal cord. The graded transcriptome of dorsal horn of the ipsilateral lumbar spinal cord was compared with that in the blood, identifying chemokines and transcription factors as potential blood-borne …