Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"nitrosative stress response"”.
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Regulation of flagellin glycosylation genes in Campylobacter jejuni: influence of NssR, the nitrosative stress response regulator.
… of flagellin glycosylation remain unclear. The response to nitric oxide stress in C. jejuni is regulated by NssR, which also regulates a small number of genes in the flagellin glycosylation locus; an nssR mutant has defective motility. This work aims to elucidate the mechanisms by which NssR …
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HcpR of Porphyromonas gingivalis utilizes heme to bind NO
… mechanisms allowing for protection against such stress remain poorly understand. HcpR is an FNR-CRP family regulator that has been implicated in regulation of the nitrosative stress response. In this study we characterize the biochemical properties of HcpR. It is a homo-dimer that is composed of …
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Characterization of the MexT Regulator of the mexEF-oprN Multidrug Efflux Operon of Pseudomonas aeruginosa
… As nitration is a well-known result of nitrosative stress, a role for xenB (and the co-regulated mexEF-oprN and PA2813-2812-2811) in a nitrosative stress response was hypothesized and tested. Using S-nitrosoglutathione (GSNO) as a source of nitrosative stress, expression of mexEF-oprN, …
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Biogenesis of iron-sulfur clusters and intracellular iron metabolism
… FtnA is capable of buffering iron when oxidative stress disrupts nascent [Fe-S] clusters and alleviates the production of hydroxyl radicals. Moreover, when physiological conditions return, IscA is able to retrieve iron from FtnA for [Fe-S] cluster assembly. The final part of this dissertation …