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Showing 1 to 3 of 3 for “"nicotine sensitization"”.

  1. Nicotine Sensitization in β-Arrestin 2 Knockout Adolescent Mice.

    … of D2 receptors and plays a mediating role in sensitization to psychostimulants and the opiate morphine. In this study, 3-4 week old BA-2 KO and wild type C57/B6 mice received nicotine tartarate (s.c, 0.5 mg/kg free base) for 7 or 14 consecutive days followed by a drug-free period. An acute …

    etsu Repository record for Nicotine Sensitization in β-Arrestin 2 Knockout Adolescent Mice. (opens in a new tab)

  2. Nicotine Sensitization in a Rodent Model of Schizophrenia: A Comparison of Adolescents, Adults, and Neurotrophic Factors.

    <p>The behavioral effects of nicotine on locomotor activity in a rodent model of psychosis were analyzed. This model is based on neonatal quinpriole treatment (a dopamine D2/D3 agonist) which causes increased D2 receptor sensitivity, a phenomenon known as D2 priming that is common in schizophrenia. …

    etsu Repository record for Nicotine Sensitization in a Rodent Model of Schizophrenia: A Comparison of Adolescents, Adults, and Neurotrophic Factors. (opens in a new tab)

  3. Sex Differences in Nicotine-Conditioned Hyperactivity in a Model of Dopamine D2 Receptor Priming: Roles of Dopamine D2 and D3 Receptor Subtypes.

    … investigation was to determine the effect of a nicotine-conditioned context on locomotor hyperactivity in an animal model of D2-priming, and whether conditioned hyperactivity could be blocked by the D2 antagonist eticlopride or the D3 antagonist nafadotride. D2-primed male rats showed enhanced …

    etsu Repository record for Sex Differences in Nicotine-Conditioned Hyperactivity in a Model of Dopamine D2 Receptor Priming: Roles of Dopamine D2 and D3 Receptor Subtypes. (opens in a new tab)