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Showing 1 to 20 of 58 for “"nicotinamide adenine dinucleotide"”.
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Generation of Reduced Nicotinamide Adenine Dinucleotide for Nitrate Reduction in Green Leaves
Made available in DSpace on 2014-12-10T17:12:47Z (GMT). No. of bitstreams: 1 7013381.pdf: 3547242 bytes, checksum: 7069da0393d6fdbdc2ffe93673d55ccb (MD5) Previous issue date: 1969
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Novel derivatives of nicotinamide adenine dinucleotide (NAD) and their biological evaluation against NAD-consuming enzymes
Nicotinamide adenine dinucleotide (β-NAD+) is a primary metabolite involved in fundamental biological processes. Its molecular structure with characteristic functional groups, such as the quaternary nitrogen of the nicotinamide ring, and the two high-energy pyrophosphate and nicotinamide …
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Solubilization, Reconstitution and Fractionation of the Membrane Reduced Nicotinamide Adenine Dinucleotide Oxidase of Bacillus Megaterium Km
Made available in DSpace on 2014-12-12T00:36:21Z (GMT). No. of bitstreams: 1 7105287.pdf: 4329453 bytes, checksum: 23c37bf533d20ad31c5e20aa167bc7e0 (MD5) Previous issue date: 1970
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Interactions between Folate Deficiency and β-Nicotinamide Adenine Dinucleotide Deficiency and Conformational Study of Thymidylate Synthase and its Physiological Relevance
… <p>Vitamins such as folic acid and nicotinamide (NAm) play an essential role in genome stability. Folic acid is a precursor of 5,10-methylenetetrahydrofolic acid (MTHF) that is partitioned into pathways leading to TTP or methionine synthesis. Deficiency of MTHF or imbalance in the …
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Purification of nicotinamide adenine dinucleotide phosphate- specific glutamate dehydrogenase from Chlorella sorokiniana and partial characterization of its physical, kinetic, and immunological properties
The ammonium inducible nicotinamide phosphate-specific glutamate dehydrogenase from Chlorella sorokiniana has been purified 260-fold to homogeneity. Depending on the technique used, the native enzyme appeared to have a molecular mass of 290,000 to 400,000 daltons and to be composed of subunits with …
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Development of fluorescence lifetime imaging microscopy techniques for analysis of single extracellular vesicles
… the free and protein-bound reduced forms of nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate (NAD(P)H) content of EVs derived from cells, human urine, and human serum with single EV resolution. The fluorescence lifetimes of NAD(P)H in EVs isolated from an …
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ΚΙΝΗΤΙΚΗ ΜΕΛΕΤΗ ΚΑΙ ΑΝΑΛΥΤΙΚΕΣ ΕΦΑΡΜΟΓΕΣ ΕΝΖΥΜΙΚΩΝ ΣΥΣΤΗΜΑΤΩΝ ΓΙΑ ΤΟΝ ΠΡΟΣΔΙΟΡΙΣΜΟ ΧΟΛΙΚΩΝ ΟΞΕΩΝ ΣΕ ΒΙΟΛΟΓΙΚΑ ΥΓΡΑ
… SPECIFIC OXIDATION OF THEIR HYDROXYL GROUPS BY NICOTINAMIDE ADENINE DINUCLEOTIDE (B-NAD+) OR BY B-NADP+ IN THE PRESENCE OF HYDROXYSTEROID DEHYDROGENASES (HSD) AND ON THE FLUORIMETRIC MONITORING OF THE PRODUCED NADH OR NADPH. THE PRESENT DISSERTATION CONTRIBUTES TO THE EXTENSION OF OUR KNOWLEDGE …
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Coenzyme engineering of NAD(P)+ dependent dehydrogenases
Coenzyme nicotinamide adenine dinucleotide (NAD, including the oxidized form-- NAD+ and reduced form--NADH) and the phosphorylated form--nicotinamide adenine dinucleotide phosphate (NADP, including NADP+ and NADPH) are two of the most important biological electron carriers. Most NAD(P) dependent …
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Study of a microbial commensalism
… exhibit a growth response toward nicotinic acid, nicotinamide, or nicotinamide adenine dinucleotide was demonstrated, suggesting that the stimulatory factor formed by the yeast was a compound of this group. The amount of stimulatory factor formed by the yeast in pure culture after 48 hr …
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Investigating the Role of PARylation in Regulating Skeletal Muscle Mass and Function in Healthy Mature Mice
… dependent on the transfer of ADPr units from nicotinamide adenine dinucleotide (NAD+) on to a plethora of biomolecules (i.e., proteins, DNA, RNA, etc.) in response to physiological stressors (i.e., nutrient deprivation, oxidative stress, DNA strand breaks). Poly-ADP-ribosylation (PARylation) …
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The impact of NOX4 deficiency on sexually dimorphic lipid handling in HFD-challenged mice
… of proteins that regulate nutrient metabolism. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4) is a dynamic, pleiotropic enzyme that generates ROS in response to nutrient levels. Here we demonstrate, particularly in the liver, skeletal muscle, and bone marrow, that in …
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THE ROLE OF NADPH OXIDASE IN NEURITE OUTGROWTH AND ZEBRAFISH NEURODEVELOPMENT
Nicotinamide adenine dinucleotide phosphate oxidases (NOX) are a family of enzymes that produce reactive oxygen species (ROS). The first NOX enzyme was discovered in leukocytes and associated with host defense in the immune system. Subsequent findings of ROS production in non-immune cells led to …
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Investigation of the mechanism of action of pep carboxylase
… conditions, malate dehydrogenase and reduced nicotinamide-adenine dinucleotide were added in both assays to convert oxaloacetic acid to malic acid, which is stable. One assay method involves the measurement of the incorporation of C¹⁴-bicarbonate into malic acid and the other …
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A study of succinic dehydrogenase, indole acetic acid oxidase, nitrate reductase and cytochrome c reductase in Hygrophorus Conicus
… blue, the former was found to be the best. Nicotinamide adenine dinucleotide (NAD⁺) was a necessary cofactor for the enzyme and could be readily dissociated from the enzyme. The enzyme has the properties of a high molecular weight nucleo- or lipoprotein.</p> <p>The presence of two kinds of …
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Label-free multiphoton microscopy for imaging transient metabolic dynamics in living cells and tissue
… lifetime imaging microscopy (2P-FLIM) of reduced nicotinamide adenine dinucleotide (NADH). This autofluorescent co-enzyme is involved in both aerobic and anaerobic metabolic processes which can be differentiated utilizing this advanced imaging approach. This thesis first presents a study of cell …
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The role of NAD+ compartmentation and dynamics in Arabidopsis thaliana
Nicotinamide adenine dinucleotide (NAD+) is a fundamental coenzyme required to regulate plant central metabolism and redox status homeostasis. Plants produce NAD+ via de novo and salvage pathways. Despite early steps of the two pathways occur in different subcellular compartments, de novo in …
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Properties of NadV / NatV Proteins in a Pyridine Nucleotide (NAD+) Scavenging System Encoded by Vibriophage KVP40
… to be involved in the synthesis and recycling of nicotinamide adenine dinucleotide (NAD+). Comparison with proteins of known function indicates that NadV possesses a nicotinamide phosphoribosyl-transferase domain (NAmPRTase) that converts nicotinamide (NAm) to nicotinamide mononucleotide (NMN). …
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Modulation of Transcription Factor Chromatin Association and Gene Transcription Program in Embryonic Stem Cell and Triple Negative Breast Cancer by Poly (ADP-Ribose) Polymerase 1
… the transfer of ADP-ribose (ADPR) units from nicotinamide adenine dinucleotide (NAD+) onto target gene regulatory proteins, thereby modulating their activities. Although great strides have been made in the past decade in deciphering the seemingly opposing and varied roles of PARP-1 in gene …
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