Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 20 for “"never-smokers"”.
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Never Smokers -- Are They More Sensitive to the Respiratory Health Effects of Ambient Air Pollution?
… study population consists of subjects who have never smoked and who have not changed their primary residence since enrollment in the study. This study specifically assessed chronic exposure to ambient particulate and gaseous pollutants (PM<sub>2.5</sub> and O<sub>3</sub>) by utilizing AHSMOG-2 …
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Are Antinuclear Antibodies and Rheumatiod Factor Positivity More Prevalent in Apparently Healthy Smokers Compared to Ex-Smokers and Never Smokers?
… with past and current second hand smoke. For never smokers there was an interaction of second hand smoke exposure with age. Those not exposed to second hand smoke showed increasing probability of ANA positivity with age. Those exposed to second hand smoke showed no such increase (0/?=0.908, …
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Lung Cancer Stigma: Associated Variables and Coping Strategies
… study suggest that, while current and former smokers report significantly greater rates of Personal Responsibility and Regret when compared to never smokers, smoking status did not significantly affect the level of Medical Stigma reported by lung cancer survivors. The most common themes …
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Examination of gene deletion as a mechanism of RBM5 downregulation in tobacco smoke-associated lung cancer
… expression in most lung cancers, especially in smokers, that may result from gene deletion. The objective of this study was to determine if significantly decreased levels of RBM5 expression in the lung cancers of smokers was related to RBM5 deletion. Using DNA from patient lung tissue, RBM5 gene …
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Values And Problem Behaviors In Hong Kong Adolescents
… alcohol use were reliable predictors of current smokers from never smokers, while the values orientation of openness to change, school band level, and alcohol use were reliable predictors of not-current smokers from never smokers. These variables accounted for a total of 23.5% of the variance …
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Effects of Cigarette Smoking on Neurocognitive Performance in Dementia Patients
… administered to two groups of dementia patients, never smokers and current/former smokers. Hierarchical linear regression analysis was used to test smoking status as a predictor of functioning in each of these four cognitive domains after controlling for potentially confounding factors such as …
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An investigation of the contribution of cigarette smoking and human papillomavirus infection to the epigenetic modulation of cellular genes in cervical epithelium
… intercourse. I have shown that compared with never-smokers, women who first started to smoke during follow-up had an increased risk of acquiring methylation of the tumour suppressor gene (TSG), CDKN2A (odds ratio=3.67; 95% confidence interval: 1.09 to 12.33; p=0.04). I was also able to show …
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Lung function in smokers - Aspects on COPD diagnosis and associations to atherosclerosis and alcohol consumption
… Pulmonary Disease (COPD) affects mainly smokers and is characterized by airflow obstruction, assessed using one of two major diagnostic spirometric criteria. Aspects of lung function besides spirometry in smokers fulfilling none, either or both of the spirometric criteria for COPD are not …
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Association of early-life tobacco exposure with Cardiovascular-Kidney-Metabolic (CKM) syndrome risk : is accelerated biological aging a mediating pathway?
… ProtAgeGap; childhood smoking initiation (vs. never smokers) was associated with 1.60-year and 0.64-year accelerations, respectively, with dose-response trends. The combined exposure showed the strongest associations (PhenoAgeAccel: 1.73 years; ProtAgeGap:0.75 years). The association with …
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The Public Health Impact of Maternal Smoking Cessation during Pregnancy : The San Bernardino County Experience
… smoking during pregnancy or by 25 mothers being never smokers during pre-pregnancy.</p> <p>The second study among 4,059 women reporting tobacco use in San Bernardino County found a dose-response relationship for prenatal care initiation in which women were more likely to quit smoking for every …
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Genetic Predictors of Clinical Outcomes In Non-Small Cell Lung Cancer Patients
… inflammation-related SNPs in NSCLC patients in never smokers. Lung cancer in never smokers has been increasingly recognized as distinct disease from that in ever-smokers. A two-stage study was performed using a discovery population from MD Anderson (411 patients) and a validation population from …
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Epidemiological risk factors, related biomarkers and oesophageal adenocarcinoma survival
… in the moderate drinkers compared to light/never drinkers (HR 1.34 95% CI 0.95-1.89 I2=0%). <br/><br/>Given the small pool of evidence identified in the systematic review, a population-based cohort study in Northern Ireland was performed to examine the association between alcohol …
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Metabolic and Lifestyle related risk factors for pancreatic cancer
… may increase the risk of pancreatic cancer in never smokers and in low alcohol consumers. High mid-blood pressure, high fasting glucose and the metabolic syndrome as an entity are associated with an increased risk of pancreatic cancer in women. In men, high mid-blood pressure is associated with …
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Cardiovascular Risk Genes in Prevention and Treatment Response
… (P=0.012). The risk conferred by rs4977574 in never-smokers (n=9642; Hazard-ratio(HR) per risk-allele(CAD)=1.26; 95%CI:1.13-1.40; HR per risk-allele(CVD-mortality)=1.40; 95%CI:1.20-1.63) was attenuated in smokers (n=7000; HR per risk-allele(CAD)=1.05; 95%CI:0.95-1.16; HR per …
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The Impact of Study Methodology on Studying Genetic and Environmental Risk Factors for the Inflammatory Bowel Diseases
… vs. separately analyzing current, former, and never smoking). Using a case-only study design (Chapter Four), the impact of age at diagnosis was explored as a potential mechanism for the negative interaction between NOD2 and smoking. Age at diagnosis exhibits opposing trends in the proportion of …
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T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro
… tended to be higher in COPD patients than in smokers and never-smokers and constituted of a B-cell core surrounded by T-cells of mainly CD4+ phenotype. In blood the number of CD4+ T-cells was elevated in smokers and CD69 expression on CD4+ T-cells in current smokers correlated with FEV1 …
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Lung mechanics in the aging lung and in acute lung injury. Studies based on sinusoidal flow modulation.
… values, based on 60 healthy 20 65 year old never-smokers, are presented for Pel/V, Pel/C and Pel/R curves. After normalization to lung size women and men had similar lung mechanics. By relating the Pel/V, Pel/C and Pel/R curves to age and lung size normal ranges were importantly narrowed. …
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The impact of tobacco control policies on university students' smoking in Ontario
… young adults have the highest proportion of smokers of all age cohorts at 26%. A growing body of evidence shows that smoking restrictions and other tobacco control policies can reduce tobacco use and consumption among adults and deter initiation among youth; whether young adult university …
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Characterising epithelial to mesenchymal transition and pro-fibrotic processes in chronic obstructive pulmonary disease
… were made between control groups: non-smokers (NS), current smokers (CS) ex-smokers (EXS), and COPD patients: COPD current smokers (CCS) and COPD ex-smokers (CEX). Identified regions of EMT tissue were laser capture microscopy dissected, RNA isolated, and target genes assessed by …
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Epidemiology of non-squamous non-small cell lung cancer in New Zealand: A focus on EGFR gene mutation
… Europeans; and only 1.25 times higher for ever-smokers (i.e. current smokers and ex-smokers) than never-smokers. The ASR of EGFR mutation-negative NSCLC was 17.39 (16.75-18.02) per 100,000 person-years overall, showing contrasting patterns of relationships among subgroups compared to EGFR …